chromium hexavalent ion

03/01/1997 - "Understanding this variability in chromium(VI) reactions may help to resolve the conflicting results from in vitro studies that are aimed at deciphering mechanisms of chromium(VI)-induced cancers."
12/01/2023 - "EPA has recently concluded that Cr(VI) acts through a mutagenic MOA based, in part, on scoring numerous in vivo genotoxicity studies as having low confidence; and therefore derived a cancer slope factor (CSF) of 0.5 (mg/kg-day)-1, equivalent to ∼0.07 ppb. "
06/19/2023 - "Recent studies revealed that chronic exposure of human bronchial epithelial cells (BEAS-2B, B2B) to Cr(VI) activated several signaling pathways and induced cell malignant transformation and tumor growth. "
03/15/2021 - "The present study provides valuable clues for elucidation of the carcinogenic mechanism of Cr(VI), especially for further prevention and targeted treatment of Cr(VI)-related cancer."
01/01/2021 - "Conclusion: A causal relation between Cr(VI) exposure and SDC, a rare cancer, cannot be demonstrated on an individual basis but detection in a population-based study is also unlikely because of the extremely low prevalence. "

11/01/2003 - "The aim of the study was to determine efficacy of NaQSA in treatment of acute poisoning with a hexavalent chromium compound. "
06/01/2022 - "Additionally, this study also provided a theoretical basis for relieving Cr (VI) poisoning from the perspective of gut microbiota."
11/01/2020 - "A new method and experimental basis were provided to the future study of Cr(VI) poisoning in broilers."
11/01/2020 - "AMPK pathway and ACACA/CPT1A two genes were selected to study the prevention and treatment of nano-Se on Cr(VI) poisoning in broilers and its molecular mechanism. "
11/01/2020 - "Nano-Se was chosen to study the antagonism of Cr(VI) poisoning in broilers. "

07/01/2012 - "However, restoration of physiological levels of Asc (≈ 1 mM) completely eliminated Cr(VI) hypersensitivity of XRCC1 knockdown. "
11/01/2021 - "In March 2014, the European Commission issued a new regulation restricting the content of hexavalent chromium (Cr) in leather to no more than 3 mg/kg. We previously performed a questionnaire study in January 2014 to characterize our patients with Cr contact allergy prior to regulatory intervention. "
05/01/1991 - "Multicenter patch test titration studies in human subjects using an incidence of positive patch tests of 10% or less showed that the threshold for skin hypersensitivity reactions to hexavalent chromium was determined to be of the order 0.001%, equivalent to 10 ppm or 10 mg/kg or 10 mg/L.(ABSTRACT TRUNCATED AT 250 WORDS)"
07/01/2021 - "(B) Seedlings of SB showed hypersensitivity to 200 μM Cr(VI) compared to B-385 in terms of primary root growth inhibition, which was higher in SB than B-385. "
07/01/2021 - "Our results show that SB's seedlings exhibit hypersensitivity as a higher root elongation inhibition than B-385 under different Cr(VI) concentrations. "

06/01/1994 - "The data from these studies were used to assess the risk of developing allergic contact dermatitis due to contact with Cr(VI) and Cr(III) in soil. "
11/01/2020 - "The persistent, difficult-to-treat, allergic contact dermatitis from hexavalent chromium in European construction workers has diminished significantly since the legislative measurements that came into force in January 2005. "
01/01/2020 - "Allergic contact dermatitis caused by Cr(VI) is often severe and difficult to treat. "
11/27/2018 - "Many cement workers suffer from Cr(VI)-induced allergic contact dermatitis (ACD), and prevention and therapeutic strategies are still lacking. "
06/01/2018 - "Since the legislation to reduce Cr(VI) in cement was introduced in 1989, we rarely see allergic contact dermatitis caused by cement. "

04/09/2021 - "The results suggest that short-term exposure to intranasal Cr(VI), in theses doses, does not trigger a major brain injury in rats; however, observation of more toxic alterations in a time-dependent manner is a threat of more sever toxicity upon longer exposure."
04/09/2021 - "A previous study of our team described a brain injury induced by acute intranasal instillation of Cr(VI) in rats, which was characterized by oxidative stress and inflammation. "
12/01/2021 - "Exposure to chromium VI dust among workers has been reported and induced brain injury, as the absorption of chromium through the nasal membrane has been found to deliver it directly to the brain. "
07/01/2017 - "The present study was designed to scrutinize the possible protective effects of caffeic acid phenethyl ester (CAPE), a bioactive phenolic of propolis extract, on Cr(VI)-induced brain injury in rats, with an emphasis on the JAK/STAT signaling pathway. "