|1.||Lazareva, N A: 2 articles (01/2006 - 09/2004)|
|2.||Zdobnova, I M: 2 articles (01/2006 - 09/2004)|
|3.||Zarubenko, I I: 2 articles (01/2006 - 09/2004)|
|4.||Feng, Zheng: 2 articles (12/2004 - 11/2004)|
|5.||Zhang, Jun-Tian: 2 articles (12/2004 - 11/2004)|
|6.||Zhang, Jing: 1 article (08/2014)|
|7.||Li, Jingmin: 1 article (08/2014)|
|8.||Xu, Zhexue: 1 article (08/2014)|
|9.||Teng, Jing: 1 article (08/2014)|
|10.||Liu, Lingyun: 1 article (06/2014)|
|1.||Alzheimer Disease (Alzheimer's Disease)
06/01/2014 - "Single rAAV-HIF-1α administration resulted in decreased apoptosis of hippocampal neurons in an Alzheimer's disease rat model established by intracerebroventricular injection of aggregated amyloid-beta protein (25-35). "
05/01/2013 - "L-1 Abeta25-35 was used to treat SH-SY5Y cells for 24 hours, in order to establish the Alzheimer's disease (AD) model. "
09/01/2008 - "The optimal concentration and treating time of Abeta25-35 for Alzheimer's Disease cellular model as well as those of WEAG were measured by flow cytometer. "
06/10/2008 - "Injection of beta-amyloid (25-35) (100 nmol or 10 nmol i.c.v.), a peptide that aggregates in brains of Alzheimer's disease patients, impaired LTP. "
05/01/2007 - "Selective sparing of SST-positive neurons at lower concentrations of Abeta25-35 at early time points directly correlates with the pathophysiology of Alzheimer's disease."
11/01/2004 - "Rat pheochromocytoma (PC12) cells treated with either Abeta25-35 or Abeta1-42 underwent apoptosis. "
12/05/2001 - "In our experiments, it was found that the neurons of cortex and the PC12 (pheochromocytoma) cells could be protected from the cytotoxicity of beta-amyloid 25-35 in presence of GIF and its domains. "
06/01/2000 - "In an effort to generate novel inhibitors of Abeta neurotoxicity and/or aggregation, a mixture-based synthetic combinatorial library composed of 23 375 imidazopyridoindoles was generated and screened for inhibition of Abeta25-35 neurotoxicity toward the rat pheochromocytoma PC-12 cell line. "
10/29/2004 - "In this study, rat pheochromocytoma (PC12) cells were exposed to Abeta25-35 and confirmed free radical generations using two kinds of spin trap agents, 5,5-dimethyl-1-pyrroline-N-oxide; DMPO and alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone; POBN. "
09/01/2013 - "The dementia rat model was established by injecting Abeta25-35 in hippocampus. "
05/01/2013 - "The dementia model rats were established by injecting Abeta25-35 10 microLg into bilateral hippocampus. "
07/01/2008 - "Immunohistochemistry revealed obvious p38 expression in the dementia group 4 days after Abeta25-35 injection, which increased significantly with the passage of time (P<0.01). "
07/01/2008 - "On days 7 and 14 following Abeta25-35 injection, the training times, error number and total reaction time were significantly higher in dementia group than in saline group (P<0.05), but all these indices were significantly lowered in the inhibitor group as compared with the dementia group (P<0.05). "
07/01/2008 - "Seventy-two adult SD rats were randomized equally into 4 groups, and a single-dose injection of Abeta25-35 (dementia group), normal saline (saline group), SB203580 (inhibitor group), or DMSO (inhibitor control group) was administered into the lateral cerebral ventricle. "
|4.||Astrocytoma (Pilocytic Astrocytoma)
12/01/2004 - "We found that rat astroglioma C6 cells treated with Abeta25-35 or Abeta1-42 undergo apoptosis and that melatonin pretreatment at 10(-5), 10(-6), and 10(-7) M significantly attenuates Abeta25-35- or Abeta1-42-induced apoptosis. "
01/04/2005 - "In this study, we examined the effect of ZST on production of interleukin (IL)-6 and IL-8, and expression of cyclooxygenase (COX)-2 in IL-1beta and beta-amyloid [25-35] fragment (Abeta)-stimulated human astrocytoma cell line U373MG. "
04/01/2006 - "We treated LAN-5 neuroblastoma cultures with toxic amounts of Abeta25-35 amyloid peptide. "
12/01/2005 - "Incubation of Abeta25-35 with transthyretin (at transthyretin concentrations equal to CSF physiological levels) demonstrated both inhibition of red blood cells lysis and neutralization of SK-N-BE neuroblastoma cells ultrastructural apoptotic changes. "
12/01/2005 - "In view of the well-recognized literature data demonstrating that Abeta25-35 fibrillar aggregates cause in vitro cytotoxicity to human red blood cells and apoptotic changes to SK-N-BE neuroblastoma cells in cultures (ultrastructural evidence), we tested transthyretin effects on these two experimental models. "
07/01/2001 - "that Abeta can increase the expression of CP450r, SK-N-SH human neuroblastoma cells were exposed to Abeta25-35 and Abeta1-42 and then examined for induction of this enzyme in immunoblots, using specific antibodies. "
|1.||Interleukin-8 (Interleukin 8)
|4.||Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)
|6.||Insulysin (Insulin-Degrading Enzyme)
|7.||Guanosine Triphosphate (GTP)
|9.||Catechin (Z 7300)
|10.||Adenosine Triphosphate (ATP)