osteogenic growth peptide

circulating stimulator of osteoblastic activity; identical to the C-terminus of histone H4; see also osteogenin; amino acid sequence of 14 amino acids given in first source

Also Known As:

Glycine, L-alanyl-L-leucyl-L-lysyl-L-arginyl-L-glutaminylglycyl-L-arginyl-L-threonyl-L-leucyl-L-tyrosylglycyl-L-phenylalanylglycyl-

Networked: 5 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Capperucci, Caterina: 1 article (07/2006)
2.	Di Stefano, Anna: 1 article (07/2006)
3.	Ferrata, Paolo: 1 article (07/2006)
4.	Frediani, Bruno: 1 article (07/2006)
5.	Galeazzi, Mauro: 1 article (07/2006)
6.	Gambera, Dario: 1 article (07/2006)
7.	Leonini, Alessandra: 1 article (07/2006)
8.	Marcolongo, Roberto: 1 article (07/2006)
9.	Rosini, Sergio: 1 article (07/2006)
10.	Spreafico, Adriano: 1 article (07/2006)

Related Diseases

1.	Osteoporosis 01/01/2023 - "Effects of osteogenic growth peptide C-terminal pentapeptide and its analogue on bone remodeling in an osteoporosis rat model." 01/01/2023 - "This study aimed to explore the effects of osteogenic growth peptide C-terminal pentapeptide (G36G), and its analog G48A on bone modeling in rats with ovariectomy-induced osteoporosis. " 07/01/2006 - "Osteogenic growth peptide effects on primary human osteoblast cultures: potential relevance for the treatment of glucocorticoid-induced osteoporosis."
2.	Femoral Fractures (Femoral Fracture) 01/01/2000 - "In this study, the effect of exogenous osteogenic growth peptide on the healing of femoral fractures in rats was investigated. "
3.	Primary Myelofibrosis (Myelosclerosis) 04/01/2003 - "Carboxy-terminal fragment of osteogenic growth peptide in vitro increases bone marrow cell density in idiopathic myelofibrosis."
4.	Wounds and Injuries (Trauma) 01/01/2000 - "Osteogenic growth peptide, a histone H4-related, 14-amino-acid peptide, is an active mediator of local, as well as systemic, osteogenic activity in response to marrow ablation, trauma, and blood loss. "
5.	Body Weight (Weight, Body) 07/01/1997 - "The results showed that animals that sustained acute blood loss (1% or 3% body weight) or injury to their tibial bone marrow had statistically significant increases in mineral appositional rate, osteoblast number, and serum levels of osteogenic growth peptide. "

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Minerals
3.	Histones (Histone)
4.	Glucocorticoids

Related Therapies and Procedures

1.	Ovariectomy (Oophorectomy)