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mucin sulfatase

Also Known As:

mucin sulphatase; sulfomucin sulfatase

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Esterases: 1574
      - Sulfatases: 574
        mucin sulfatase: 4

Experts

1.	Campbell, Barry J: 1 article (10/2007)
2.	Hart, C Anthony: 1 article (10/2007)
3.	Kertesz, Michael A: 1 article (10/2007)
4.	Thibault, Christelle: 1 article (10/2007)
5.	Tralau, Tewes: 1 article (10/2007)
6.	Vuilleumier, Stéphane: 1 article (10/2007)

Related Diseases

1.	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 04/01/1995 - "A possible role for faecal mucin sulphatase in the pathogenesis of inflammatory bowel disease has therefore been explored. "
2.	Dental Caries (Decay, Dental) 01/01/1994 - "Streptococcal mucin-sulphatase may contribute to the destruction of salivary mucins and mitigate their protective functions in the oral cavity, and be a determinant in the development of dental caries."
3.	Cystic Fibrosis (Mucoviscidosis) 10/01/2007 - "aeruginosa E601, a cystic fibrosis isolate that displays mucin sulfatase activity, and in P. "
4.	Crohn Disease (Crohn's Disease) 04/01/1995 - "Faecal mucin sulphatase activity was not significantly increased in Crohn's disease (median 36.6, range 5.7-106.6; 95% CI: 22.9 to 65.3 units/g, n = 14). "
5.	Ulcerative Colitis 04/01/1995 - "Longitudinal studies in patients with ulcerative colitis show fluctuations of faecal mucin sulphatase activity corresponding to clinical disease activity in six of seven patients. " 04/01/1995 - "Increased faecal mucin sulphatase activity in ulcerative colitis: a potential target for treatment." 04/01/1995 - "The increased faecal mucin sulphatase activity in ulcerative colitis could be the result of greater intraluminal substrate (mucin) availability leading to bacterial enzyme induction, but would probably result in more rapid degradation of secreted mucin and represents a potential target for treatment." 04/01/1995 - "Faecal mucin sulphatase activity assayed using 35S mucin as substrate was increased in ulcerative colitis (median 80.2 units/g pellet weight (range 6.9-1063; 95% confidence intervals (CI): 45.2 to 293.8, n = 22) compared with 11.3 units/g (range 3.0-53.5; 95% CI: 8.7 to 29.8, n = 17) in healthy controls (p < 0.01), where one unit released 1000 dpm free sulphate/hour from 35S mucin (1680 dpm/microgram). "

Related Drugs and Biologics

1.	Mucins
2.	Suspensions