longestin

trypanocidal agent; isolated from Steptomyces argenteolus; inhibits brain calcium- and calmodulin-dependent cyclic nucleotide phosphodiesterase; structure given in first source

Also Known As:

KS 505a; KS-505a; beta-D-Glucopyranosiduronic acid, 1-carboxy-2,3,4,4a,4b,5,6,6a,6b,7,8,8a,8b,9,10,10a,14,16,17,17a,17b,18,19,19a,19b,20,21,21a,21b,22,23,23a-dotriacontahydro-14-hydroxy-8a,10a-bis(hydroxymethyl)-14-(3-methoxy-3-oxopropyl)-1,4,4a,6,6a,17b,19b,21b-octameth

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Neuroblastoma 09/01/1993 - "Neurite formation in NG108-15 neuroblastoma x glioma hybrid cells by KS-505a, a potent inhibitor of brain cyclic nucleotide phosphodiesterase."
2.	Glioma (Gliomas) 09/01/1993 - "Neurite formation in NG108-15 neuroblastoma x glioma hybrid cells by KS-505a, a potent inhibitor of brain cyclic nucleotide phosphodiesterase."

Related Drugs and Biologics

1.	Phosphoric Diester Hydrolases (Phosphodiesterases)
2.	Cyclic Nucleotides

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