prulifloxacin

structure given in first source

Also Known As:

6-fluoro-1-methyl-7-(4-(5-methyl-2-oxo-1,3-dioxelen-4-yl)methyl-1-piperazinyl)-4-oxo-4H-(1,3)thiazeto(3,2-a)quinoline-3-carboxylic acid; NM 441; NM-441; NM441; 1H,4H-(1,3)Thiazeto(3,2-a)quinoline-3-carboxylic acid, 6-fluoro-1-methyl-7-(4-((5-methyl-2-oxo-1,3-dioxol-4-yl)methyl)-1-piperazinyl)-4-oxo-

Networked: 63 relevant articles (14 outcomes, 21 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperazines: 26
    - prulifloxacin: 63
  - Dioxoles
    - Dioxolanes: 3
      - prulifloxacin: 63
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Quinolones: 2938
        Fluoroquinolones: 5348
        prulifloxacin: 63

Experts

1.	Dionisio, Paolo: 6 articles (02/2012 - 01/2002)
2.	Ruggieri, Alessandro: 4 articles (01/2021 - 01/2007)
3.	Picollo, Rossella: 4 articles (09/2018 - 01/2007)
4.	Cai, Tommaso: 3 articles (07/2012 - 06/2009)
5.	Rosignoli, Maria Teresa: 3 articles (02/2012 - 01/2002)
6.	Bartoletti, R: 3 articles (01/2010 - 03/2006)
7.	Salvatori, Enrica: 3 articles (02/2006 - 01/2002)
8.	Sahoo, Biswa Mohan: 2 articles (01/2022 - 01/2021)
9.	Comandini, Alessandro: 2 articles (01/2021 - 09/2018)
10.	Del Vecchio, Alessandra: 2 articles (01/2021 - 09/2018)

Related Diseases

1.	Prostatitis 04/01/2011 - "In summary, prulifloxacin appears to be a promising agent for the treatment of bacterial prostatitis and traveller's diarrhoea." 01/01/2010 - "Clinical and microbiological efficacy of prulifloxacin for the treatment of chronic bacterial prostatitis due to Chlamydia trachomatis infection: results from a prospective, randomized and open-label study." 09/01/2009 - "Re: Serenoa repens associated with Urtica dioica (ProstaMEV) and curcumin and quercitin (FlogMEV) extracts are able to improve the efficacy of prulifloxacin in bacterial prostatitis patients: results from a prospective randomised study." 06/01/2009 - "Serenoa repens associated with Urtica dioica (ProstaMEV) and curcumin and quercitin (FlogMEV) extracts are able to improve the efficacy of prulifloxacin in bacterial prostatitis patients: results from a prospective randomised study." 06/01/2007 - "Prulifloxacin versus levofloxacin in the treatment of chronic bacterial prostatitis: a prospective, randomized, double-blind trial."
2.	Infections 07/01/2012 - "Semen quality in patients with Chlamydia trachomatis genital infection treated concurrently with prulifloxacin and a phytotherapeutic agent." 02/01/2009 - "Additional research is needed to further elucidate the promising role of prulifloxacin in the treatment of infections sustained by multidrug-resistant pathogens and to consolidate the wide spectrum of activity from a clinical standpoint." 03/01/2007 - "In patients undergoing transrectal ultrasound-guided prostate biopsy, antimicrobial prophylaxis with prulifloxacin, both in single shot and 5-day administration, was found to prevent infection, with good tolerability and acceptability by the patients." 01/01/2010 - "Prulifloxacin was also equivalent to standard therapy for clinical success, as demonstrated by a decrease in the number of patients affected by CP due to Ct infection." 01/01/2010 - "Clinical and microbiological efficacy of prulifloxacin for the treatment of chronic bacterial prostatitis due to Chlamydia trachomatis infection: results from a prospective, randomized and open-label study."
3.	Chronic Bronchitis 01/01/2005 - "The findings from this lung penetration study could explain the efficacy of once-daily prulifloxacin 600mg observed in clinical trials conducted in patients with exacerbation of chronic bronchitis." 01/01/2021 - "Prulifloxacin Effectiveness in Moderate-to-Severe Acute Exacerbations of Chronic Bronchitis: Α Noninterventional, Multicentre, Prospective Study in Real-Life Clinical Practice-The "AIOLOS" Study." 01/01/2021 - "Real-world evidence regarding the effectiveness of prulifloxacin in the treatment of acute exacerbations of chronic bronchitis (AECB) is limited. " 01/01/2007 - "Prulifloxacin: a brief review of its potential in the treatment of acute exacerbation of chronic bronchitis." 01/01/2006 - "Prulifloxacin: a new fluoroquinolone for the treatment of acute exacerbation of chronic bronchitis."
4.	Urinary Tract Infections (Urinary Tract Infection) 10/01/2007 - "In this study, we focused on the therapeutic efficacy of prulifloxacin (PUFX) against Pseudomonas aeruginosa OP 14-210, isolated from a patient with complicated urinary tract infection. " 04/01/2011 - "In this review, PubMed and Scopus databases were searched for potential uses of prulifloxacin beyond respiratory and urinary tract infections. " 04/01/2011 - "Prulifloxacin: a review focusing on its use beyond respiratory and urinary tract infections." 06/01/2007 - "Minimum inhibitory concentrations (MICs) and mutant prevention concentrations (MPCs) of prulifloxacin against 30 strains of Escherichia coli isolated from urinary tract infections as well as the 'biological cost' related to acquisition of resistance to the same drug in 10 uropathogenic E. " 06/01/2007 - "In vitro activity of prulifloxacin against Escherichia coli isolated from urinary tract infections and the biological cost of prulifloxacin resistance."
5.	Cystitis 11/01/2009 - "In order to evaluate the tolerability and efficacy of a 14-day course of prulifloxacin orally administered once daily, 51 young female patients, attending the same STD center between may and June 2007 for symptoms of cystitis, with a history of recurrent UTI and urine culture positive for uropathogens, were enrolled in this prospective study. " 11/01/2009 - "14-day prulifloxacin treatment of acute uncomplicated cystitis in women with recurrent urinary tract infections: a prospective, open-label, pilot trial with 6-month follow-up." 01/01/2019 - "Potentially effective options to prevent symptoms of cystitis are BCG dose reduction, intravesical hyaluronic acid instillations and oral prulifloxacin or ofloxacin administration. "

Related Drugs and Biologics

1.	Ciprofloxacin (Cipro)
2.	Anti-Bacterial Agents (Antibiotics)
3.	Curcumin
4.	ulifloxacin
5.	Levofloxacin (Levaquin)
6.	Amoxicillin-Potassium Clavulanate Combination (Co-amoxiclav)
7.	Pefloxacin
8.	Ritonavir (Norvir)
9.	Ribavirin (Virazole)
10.	Hydroxychloroquine (Plaquenil)

Related Therapies and Procedures

1.	Therapeutics
2.	Catheters
3.	Suburethral Slings (Tension-Free Vaginal Tape)
4.	Antibiotic Prophylaxis
5.	Drug Tapering