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8- tert- butyl- 6,7- dihydropyrrolo(3,2- e)- 5- methylpyrazolo(1,5- a)pyrimidine- 3- carbonitrile

structure given in first source

Also Known As:

LP 805; LP-805; 6H-Pyrazolo(1,5-a)pyrrolo(3,2-e)pyrimidine-3-carbonitrile, 8-(1,1-dimethylethyl)-7,8-dihydro-5-methyl-

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrazoles: 61
      - 8-tert-butyl-6,7-dihydropyrrolo(3,2-e)-5-methylpyrazolo(1,5-a)pyrimidine-3-carbonitrile: 2
  - Pyrimidines: 510
    - 8-tert-butyl-6,7-dihydropyrrolo(3,2-e)-5-methylpyrazolo(1,5-a)pyrimidine-3-carbonitrile: 2

Experts

1.	Funayama, Norio: 1 article (04/2003)
2.	Ikegami, Kenji: 1 article (04/2003)
3.	Imaizumi, Michiru: 1 article (04/2003)
4.	Ishida, Fumitaka: 1 article (04/2003)
5.	Kawatani, Masahito: 1 article (04/2003)
6.	Nimura, Toshie: 1 article (04/2003)
7.	Sato, Tomoya: 1 article (04/2003)

Related Diseases

1.	Abnormal Reflex (Hyperreflexia) 04/30/2003 - "Intravesical administration of LP-805 urine induced hyperreflexia of the micturition reflex in normal rats. "
2.	Ischemia 11/05/1991 - "In conclusion, LP-805 may reduce the influence of ischemia on the myocardium." 11/05/1991 - "LP-805 attenuated the decrease in myocardial pH induced by ischemia in a dose-dependent manner. " 11/05/1991 - "After 30 min of ischemia, either saline containing 0.1 N HCl or 10, 30 or 100 micrograms/kg of LP-805 was injected intravenously. " 11/05/1991 - "Attenuation of ischemia-induced regional myocardial acidosis by LP-805, a newly developed vasodilator, in dogs."
3.	Acidosis 11/05/1991 - "Attenuation of ischemia-induced regional myocardial acidosis by LP-805, a newly developed vasodilator, in dogs."
4.	Crystalluria 04/30/2003 - "The rats, which were given LP-805 (100 mg/kg/day) orally for 12 days, voided crystalluria. "

Related Drugs and Biologics

1.	Vasodilator Agents (Vasodilators)

Related Therapies and Procedures

1.	Intravesical Administration