phosphoprotein phosphatase inhibitor 1

a 32 kDa heat-stable protein whose activity is regulated by cAMP-dependent pathway; an antagonist of phosphoserine phosphatase

Also Known As:

PHI-1; inhibitor I1, phosphoprotein phosphatase; inhibitor-1, PP1

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Starvation 01/01/2003 - "The EXO gene, which forms part of a small gene family in Arabidopsis, is structurally related to the tobacco PHI-1 gene, which is re-activated in cultured cells following release from phosphate starvation-induced cell cycle arrest. "
2.	Hypoxia (Hypoxemia) 04/15/2005 - "To determine if prolyl 4-hydroxylase (PHD) inhibition could augment hypoxia-inducible factors (HIFs) and expression of angiogenic proteins essential for lung development, HIF-1alpha and -2alpha proteins were assessed in human developing and adult lung microvascular endothelial cells and alveolar epithelial-like cells treated with either the HIF-PHD-selective inhibitor PHI-1 or the nonselective PHD inhibitors dimethyloxaloylglycine (DMOG) and deferoxamine (DFO). "

1.	Prolyl Hydroxylases (Prolyl Hydroxylase)
2.	Angiogenic Proteins
3.	Proteins (Proteins, Gene)
4.	Phosphates (Orthophosphate)
5.	Deferoxamine (Desferal)