|1.||Motion Sickness (Airsickness)
10/01/1991 - "In experiments with cats, idaverine failed to prevent motion sickness at doses from 0.03 to 3 mg/kg. These results are interpreted to implicate M3-receptors in the motion sickness suppressant effect of antimuscarinic drugs."
10/01/1991 - "Idaverine, an M2- vs. M3-selective muscarinic antagonist, does not prevent motion sickness in cats."
10/01/1991 - "In this study, the affinity profile of idaverine for the M1- (neuronal tissue), M2- (heart) and M3- (glandular tissue/nonvascular smooth muscle) muscarinic receptors was examined by means of radioligand binding and in vitro organ bath experiments in order to use the compound for the investigation of the muscarinic receptor subtype involved in motion sickness. "
|1.||Muscarinic Receptors (Muscarinic Acetylcholine Receptor)