bromofosfamide

structure given in first source

Also Known As:

CBM-11; N,N'-bis(2-bromoethyl)phosphorodiamidic acid; N,N'-bis(BrEt)isophosphoramide; N,N'-bis-(2-bromoethyl)phosphorodiamidic acid; 2H-1,3,2-Oxazaphosphorin-2-amine, N-(2-bromoethyl)-3-(2-chloroethyl)tetrahydro-, 2-oxide

Networked: 4 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Kobylińska, K: 2 articles (01/2001 - 01/2001)
2.	Kobylińska, M: 2 articles (01/2001 - 01/2001)
3.	Sobik, B: 2 articles (01/2001 - 01/2001)
4.	Kinas, R W: 1 article (06/2001)
5.	Kuśnierczyk, H: 1 article (06/2001)
6.	Misiura, K: 1 article (06/2001)
7.	Radzikowski, C: 1 article (06/2001)
8.	Stec, W J: 1 article (06/2001)
9.	Gasiorek, M: 1 article (01/2001)
10.	Koralewski, P: 1 article (01/2001)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2001 - "(-)-(S)-Bromofosfamide ((2S)-(2-chloroethylamino)-3-(2-bromoethyl)-1,3,2-oxazaphosphorinane 2-oxide, CAS 146452-37-1, CBM-11) is a new potential anti-cancer drug, currently under investigation. " 06/01/2001 - "(S)-(-)-Bromofosfamide (CBM-11), an enantiomerically pure bromo analog of ifosfamide, was found to be potent against several model tumors in mice. " 01/01/1997 - "In this study we have compared the magnitude of urotoxic effects elicited by ifosfamide and two bromofosfamide compounds--racemate and S(-) isomer of chlorobromofosfamide (ClBrs)--selected previously on the base of their superior antitumor activity in advanced animal tumor models. "
2.	Lung Neoplasms (Lung Cancer) 01/01/2001 - "Pharmacokinetics and toxicity of oral (-)-(S)-bromofosfamide in lung cancer patients."
3.	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/01/2001 - "The pharmacokinetics and toxicity of (-)-(S)-bromofosfamide ((2S)-(2-chloroethylamino)-3-(2-bromoethyl)-1,3,2-oxazaphosphorinae 2-oxide, CAS 146452-37-1, CBM-11) were determined in ten patients with non-small cell lung cancer following an oral dose of 1.38 g/m2 B.S.A. "

Related Drugs and Biologics

1.	Ifosfamide
2.	chlorobromofosfamide