NOP-bolus regimen

chemotherapy protocol consisting of above 3 cpds; used in treatment of multiple myeloma; see also NOP protocol which uses prednisolone instead of prednisone

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Therapy Context: Research Results

Therapeutics: 1158551
- Drug Therapy: 293145
  - Combination Drug Therapy: 12066
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - NOP-bolus regimen: 1
  - Antineoplastic Protocols: 55
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - NOP-bolus regimen: 1
- Clinical Protocols
  - Antineoplastic Protocols: 55
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - NOP-bolus regimen: 1
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Anthracenes: 12
        Anthrones: 12
        Anthraquinones: 788
        Mitoxantrone: 2907
        NOP-bolus regimen: 1
- Quinones: 434
  - Anthraquinones: 788
    - Mitoxantrone: 2907
      - NOP-bolus regimen: 1
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Anthracenes: 12
    - Anthrones: 12
      - Anthraquinones: 788
        Mitoxantrone: 2907
        NOP-bolus regimen: 1
- Fused-Ring Compounds
  - Steroids: 70059
    - Pregnanes: 9
      - Pregnadienes
        Pregnadienediols
        Prednisone: 12650
        NOP-bolus regimen: 1
Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Indole Alkaloids: 200
    - Secologanin Tryptamine Alkaloids: 81
      - Vinca Alkaloids: 463
        Vincristine: 9251
        NOP-bolus regimen: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Indole Alkaloids: 200
        Secologanin Tryptamine Alkaloids: 81
        Vinca Alkaloids: 463
        Vincristine: 9251
        NOP-bolus regimen: 1
    - Indolizines: 3
      - Indolizidines: 2
        Indole Alkaloids: 200
        Secologanin Tryptamine Alkaloids: 81
        Vinca Alkaloids: 463
        Vincristine: 9251
        NOP-bolus regimen: 1

Related Diseases

1.	Multiple Myeloma 02/01/1992 - "In a phase II study, 58 patients with resistant multiple myeloma (MM) were treated with a combination chemotherapy (NOP-bolus regimen) consisting of mitoxantrone (16 mg/m2 for the first 25 patients and 12 mg/m2 for the subsequent 33), vincristine (2 mg), both as bolus injections on day 1 and prednisone (250 mg/d on d 1-4 and 17-20). "

Related Drugs and Biologics

1.	Vincristine (Oncovin)
2.	Prednisone (Sone)
3.	Mitoxantrone (Novantrone)

Related Therapies and Procedures

1.	Injections
2.	Combination Drug Therapy (Combination Chemotherapy)