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hepatic stimulator substance

a 12 to 20 kDA polypeptide with mitogenic effects on the liver; isolated from weanling rat liver

Networked: 29 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intercellular Signaling Peptides and Proteins: 29768
    - hepatic stimulator substance: 29
- Peptides: 82426
  - Intercellular Signaling Peptides and Proteins: 29768
    - hepatic stimulator substance: 29
Biological Factors: 2472
- Intercellular Signaling Peptides and Proteins: 29768
  - hepatic stimulator substance: 29

Experts

1.	An, Wei: 8 articles (01/2018 - 08/2007)
2.	Wu, Yuan: 3 articles (01/2018 - 08/2007)
3.	Theocharis, Stamatios E: 3 articles (11/2009 - 10/2002)
4.	An, W: 3 articles (12/2001 - 06/2000)
5.	Chen, L: 3 articles (12/2001 - 06/2000)
6.	Jia, Xiao-Wei: 2 articles (01/2018 - 12/2017)
7.	Zhang, Can: 2 articles (01/2017 - 08/2015)
8.	Li, Shenglan: 2 articles (08/2015 - 09/2011)
9.	Li, Wen: 2 articles (04/2013 - 09/2011)
10.	Yu, Hao: 2 articles (09/2011 - 08/2007)

Related Diseases

1.	Acute Liver Failure (Fulminant Hepatic Failure) 02/01/1992 - "[A study of the protective mechanism of hepatic stimulator substance against experimental acute liver failure in mice]." 10/01/1991 - "[Protective effect of hepatic stimulator substance against experimental acute liver failure in mice]." 06/01/2003 - "Hepatic stimulator substance administration ameliorates liver regeneration in an animal model of fulminant hepatic failure and encephalopathy." 10/01/2002 - "Hepatic stimulator substance activity in animal model of fulminant hepatic failure and encephalopathy." 04/01/1993 - "Hepatic stimulator substance protects against acute liver failure induced by carbon tetrachloride poisoning in mice."
2.	Brain Diseases (Brain Disorder) 06/01/2003 - "Hepatic stimulator substance administration ameliorates liver regeneration in an animal model of fulminant hepatic failure and encephalopathy." 10/01/2002 - "Hepatic stimulator substance activity in animal model of fulminant hepatic failure and encephalopathy."
3.	Liver Cirrhosis (Hepatic Cirrhosis) 05/01/1997 - "[Protective effects of hepatic stimulator substance on experimental liver fibrosis in rats]."
4.	Fibrosis (Cirrhosis) 08/01/2012 - "Hepatic stimulator substance alleviates toxin-induced and immune-mediated liver injury and fibrosis in rats." 11/01/2009 - "Involvement of hepatic stimulator substance in experimentally induced fibrosis and cirrhosis in the rat." 04/01/1996 - "Effects of hepatic stimulator substance, herbal medicine, selenium/vitamin E, and ciprofloxacin on cirrhosis in the rat." 04/01/1996 - "The data indicate that hepatic stimulator substance, traditional Chinese herbal medicine, selenium plus vitamin E, and ciprofloxacin significantly decrease the amount of hepatic fibrosis caused by CCl4/ethanol injury in rats." 04/01/1996 - "The aim of this study was to compare the effects of hepatic stimulator substance, traditional Chinese herbal medicine, selenium plus vitamin E, and ciprofloxacin treatment on biochemical and histological features of fibrosis in rats with carbon tetrachloride (CCl4)/ethanol-induced cirrhosis. "
5.	Reperfusion Injury 12/01/2017 - "Our previous studies have demonstrated that hepatic stimulator substance (HSS) is an antiapoptotic effector and could protect liver from ischemia/reperfusion injury. " 12/01/2017 - "Hepatic stimulator substance resists hepatic ischemia/reperfusion injury by regulating Drp1 translocation and activation." 04/01/2013 - "Adenoviral gene transfer of hepatic stimulator substance confers resistance against hepatic ischemia-reperfusion injury by improving mitochondrial function."

Related Drugs and Biologics

1.	Carbon Tetrachloride (Tetrachloromethane)
2.	Vitamin E
3.	Selenium
4.	Ciprofloxacin (Cipro)
5.	Ethanol (Ethyl Alcohol)
6.	Therapeutic Uses
7.	Intercellular Signaling Peptides and Proteins (Growth Factors)
8.	Mitogen-Activated Protein Kinases
9.	Proto-Oncogene Proteins p21(ras)
10.	Proteins (Proteins, Gene)