sulfide quinone reductase

part of the photosynthetic electron transport chain in Chlorobium; reaction occurs in the dark, in the absence of oxygen

Also Known As:

SQR enzyme; plastoquinone reductase; sulfide-quinone oxidoreductase; sulfide-quinone reductase

Networked: 15 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Oxidoreductases: 13671
    - NADPH Oxidoreductases NADH
      - Quinone Reductases: 10
        sulfide quinone reductase: 15

Experts

1.	Banerjee, Ruma: 2 articles (01/2020 - 01/2019)
2.	Baugh, Simon D P: 1 article (01/2022)
3.	Cox, Kristie D: 1 article (01/2022)
4.	Jackson, Michael R: 1 article (01/2022)
5.	Jorns, Marilyn Schuman: 1 article (01/2022)
6.	Lam, Patrick Y S: 1 article (01/2022)
7.	Polyak, Boris: 1 article (01/2022)
8.	Rashad, Adel A: 1 article (01/2022)
9.	Wakeen, Luke: 1 article (01/2022)
10.	Wang, Yihang: 1 article (12/2021)

Related Diseases

1.	Parkinson Disease (Parkinson's Disease) 01/01/2023 - "Sulfide:quinone oxidoreductase ameliorates neurodegeneration in a murine model of Parkinson's disease."
2.	Hypoxia (Hypoxemia) 01/01/2021 - "Here, we show that, in mice, rats, and naturally hypoxia-tolerant ground squirrels, the sensitivity of the brain to hypoxia is inversely related to the levels of sulfide:quinone oxidoreductase (SQOR) and the capacity to catabolize sulfide. " 03/15/2023 - "Furthermore, H 2 S oxidation by mitochondrial sulfide quinone oxidoreductase (SQOR) rather than downstream persulfides, synergizes with hypoxia to induce a reductive shift, limiting endothelial cell proliferation that is attenuated by dissipation of the mitochondrial NADH pool. " 12/01/2021 - "During hypoxia, both enzyme activity and mRNA levels of alternative oxidase (AOX) increased while the key enzymes in MSOC, sulfide: quinone oxidoreductase (SQR) and sulfur dioxygenase (SDO), were not altered. "
3.	Ethylmalonic encephalopathy 11/12/2022 - "Intestinal mucosal biopsies of 25 adults and 22 children with IBD along with those of 26 healthy controls were stained immunohistochemically for cystathionine-γ-lyase (CSE), 3-mercapto-sulfurtransferase (3-MST), ethylmalonic encephalopathy 1 protein (ETHE1), sulfide:quinone oxidoreductase (SQOR) and thiosulfate sulfurtransferase (TST). " 07/01/2012 - "The capacity of HT-29 Glc(-/+) cells to oxidize lower concentration of sulfide was associated with the expression of transcripts corresponding to the enzymes of the sulfide oxidizing unit (SOU), that is, sulfide quinone reductase (SQR), dioxygenase ethylmalonic encephalopathy, and thiosulfate sulfur transferase (TST). " 09/15/2022 - "Western blotting was used to detect the expression of the H2S-producing enzymes cystathionine β-synthase (CBS), cystathionine γ-lyase (CSE) and 3-mercaptopyruvate sulfurtransferase (3-MST), as well as several key enzymes involved in H2S degradation such as thiosulfate sulfurtransferase/rhodanese (TST), ethylmalonic encephalopathy 1 protein/persulfide dioxygenase (ETHE1) and sulfide-quinone oxidoreductase (SQR). "
4.	Mitochondrial Diseases (Mitochondrial Disease) 11/25/2020 - "This finding leads us to hypothesize that the therapeutic effects of CoQ10, frequently administered to patients with primary or secondary mitochondrial dysfunction, might be due to its function as cofactor for sulfide:quinone oxidoreductase (SQOR), the first enzyme in the sulfide oxidation pathway. "
5.	Metabolic Syndrome (Dysmetabolic Syndrome X) 07/01/2010 - "Some of these novel candidate proteins such as GFPT1, CD36, PLAA (phospholipase A(2)-activating protein), METTL7B, SLC30A1, several G signaling proteins, and the sulfide-metabolizing ETHE1 and SQRDL (sulfide-quinone reductase-like) might be considered as drug targets for the treatment of metabolic syndrome."

Related Drugs and Biologics

1.	Sulfides (Thioethers)
2.	Enzymes
3.	Proteins (Proteins, Gene)
4.	Dioxygenases
5.	Thiosulfate Sulfurtransferase (Rhodanese)
6.	Lyases
7.	Cystathionine
8.	Therapeutic Uses
9.	Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)
10.	Transferases