|1.||Prentice, Howard: 2 articles (10/2014 - 01/2013)|
|2.||Wu, Jang-Yen: 2 articles (10/2014 - 01/2013)|
|3.||Wu, J Y: 2 articles (01/2001 - 01/2001)|
|4.||Gharibani, P: 1 article (08/2015)|
|5.||Alexandrescu, A: 1 article (08/2015)|
|6.||Tao, R: 1 article (08/2015)|
|7.||Ma, Z: 1 article (08/2015)|
|8.||Prentice, H: 1 article (08/2015)|
|9.||Menzie, J: 1 article (08/2015)|
|10.||Wu, J-Y: 1 article (08/2015)|
10/01/2014 - "Then, DETC-MeSO was administered subcutaneously for 4 and 8 days with the first injection occurring 1 h before or 24 h after reperfusion in the rat middle cerebral artery occlusion stroke model. "
08/06/2015 - "Therefore, we conclude that combined treatment with both DETC-MeSO and taurine synergistically inhibits all three ER stress pathways and apoptosis and therefore can be a novel and effective treatment after ischemic stroke."
08/06/2015 - "Twenty four hours following reperfusion of a 2-h ischemic stroke, rats received either 0.56-mg/kg DETC-MeSO or 40-mg/kg of taurine, either alone or in combination, subcutaneously for 4days. "
10/01/2014 - "Mode of action of S-methyl-N, N-diethylthiocarbamate sulfoxide (DETC-MeSO) as a novel therapy for stroke in a rat model."
08/06/2015 - "We have recently reported on the efficacy of an N-methyl-d-aspartate (NMDA) receptor partial antagonist, S-Methyl-N,N-diethylthiolcarbamate sulfoxide (DETC-MeSO), in improving outcome following stroke, including reduced infarct size and calcium influx, suppressing the endoplasmic reticulum (ER) stress-induced apoptosis as well as improving behavioral outcome. "
10/01/2014 - "S-Methyl-N, N-diethylthiocarbamate sulfoxide (DETC-MeSO), the active metabolite of disulfiram, has been shown to be a partial antagonist of glutamate receptors and effective in reducing seizure. "
01/01/2001 - "In addition, DETC-MeSO pretreatment effectively prevented seizures in mice induced either by NMDA, ammonium acetate, or ethanol-induced kindling seizures, all of which are believed to be mediated by NMDA receptors. "
09/26/1997 - "Seizures caused by the glutamate analogs N-methyl-D-aspartate and methionine sulfoximine, or by hyperbaric oxygen, are prevented by DETC-MeSO, indicating that carbamoylation of glutamate receptors gives an antagonist effect. "
|3.||Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
10/01/2014 - "We also showed that DETC-MeSO can prevent gliosis. "
|3.||S-methyl N,N-diethylthiolcarbamate sulfoxide
|5.||Glutamate Receptors (Glutamate Receptor)
|7.||Granulocyte Colony-Stimulating Factor (G-CSF)
|10.||N-Methyl-D-Aspartate Receptors (NMDA Receptors)