apholate
was MH 1972-92 (see under AZIRINES 1972-90); use AZIRIDINES to search APHOLATE 1972-92
Networked: 11
relevant articles (0 outcomes,
1 trials/studies)
Bio-Agent Context: Research Results
Related Diseases
1. | Chromosome Aberrations (Chromosome Abnormalities)
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2. | Infertility (Sterility)
01/01/1970
- " Apholate-sterilized laboratory males were not only compatible with wild females but could even induce the same level of sterility in them and were fully as competetive in mating as normal wild males. " 01/01/1969
- " the polyaziridinyl compounds, non-toxic doses of apholate could produce about 100% sterility with larval treatment. " 01/01/1967
- " The investigation discussed in the present paper has shown that apholate (2,2,4,4,6,6-hexahydro-2,2,4,4,6,6-hexakis (1-aziridinyl)-1,3,5,2,4,6-triazatriphosphorine) can induce sterility rates of from 43% to 95% in Culex pipiens fatigans Wiedemann treated in the larval stage, and from 80% to 100% in C. " 07/31/1964
- " Increased resistance to the sterilizing effects of apholate was observed in two colonies of Aedes aegypti (L.) exposed in the larval stage of each generation to concentrations of apholate that induced about 90 to 40 percent sterility in the eggs laid by the ensuing adults." 01/01/1969
- " The probable reasons for the recovery from sterility of apholate-treated males and the more lasting sterility of tepa-treated males are discussed."
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3. | Neoplasms (Cancer)
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4. | Lymphopenia (Lymphocytopenia)
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5. | Leukopenia
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Related Drugs and Biologics
Related Therapies and Procedures