SDZ MKS 492

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2 relevant articles (0 outcomes, 0 trials/studies) found for this Bio-Agent

Also Known As:

(8-(1-(3,4-dimethoxyphenyl)-2-hydroxyethyl)amino)-3,7-dihydro-7-(2-methoxyethyl)-1,3-dimethyl-1H-purine-2,6-dione; MKS 492; MKS-492; SDZ MKS-492; 1H-Purine-2,6-dione, 8-((1-(3,4-dimethoxyphenyl)-2-hydroxyethyl)amino)-3,7-dihydro-7-(2-methoxyethyl)-1,3-dimethyl-, (R)-

Bio-Agent Context: Research Results

Heterocyclic Compounds: 23

2-Ring Heterocyclic Compounds

Purines: 341

Purinones

SDZ MKS 492: 2

Related Diseases

1.	Spasm (Spasms) 01/01/1991 - "SDZ MKS 492 (R(+)-(8-[( 1-(3,4-Dimethoxyphenyl)-2-hydroxyethyl)amino]-3,7-dihydro-7-(2- methoxyethyl)-1,3-dimethyl-1H-purine-2,6-dione) relaxes airway smooth muscle in vitro and impairs, or reverses, spasm of guinea-pig airways in vivo" Get all the results and reference details, order at left...
2.	Hypersensitivity (Allergy) 12/01/1993 - "Effects of MKS-492 on antigen-induced bronchoconstriction and allergic reaction in guinea pigs and rats." Get all the results and reference details, order at left...
3.	Eosinophilia 12/01/1993 - "4) MKS-492 inhibited leukotriene B4 (LTB4)-induced airway eosinophilia in guinea pigs" Get all the results and reference details, order at left...
4.	Bronchial Spasm 01/01/1991 - "Effects on bronchospasm in the guinea-pig may additionally include actions on airway hyperreactivity, since SDZ MKS 492 can inhibit the development, or expression, of airway hyperreactivity due to infusion of PAF, (+/-)isoprenaline, endotoxin or injection of immune complexes" Get all the results and reference details, order at left...
5.	Asthma (Bronchial Asthma) 01/01/1991 - "SDZ MKS 492 offers the prospect of a monotherapy for asthma, combining bronchodilator and anti-inflammatory activities with prophylactic efficacy." Get all the results and reference details, order at left...
5 Diseases and 2 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Leukotriene B4
2.	Isoproterenol (Isoprenaline)
3.	Antigens
4.	Antigen-Antibody Complex (Immune Complex)
5.	purine
5 Drugs and Important Bio-Agents and 2 more articles analyzed in the Research Interface, order at left...

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