chlorin p6

structure given in first source; a new photosensitizer for treatment of glioma tumors

Also Known As:

21H,23H-Porphine-2,20-dicarboxylic acid, 18-(2-carboxyethyl)-12-ethenyl-7-ethyl-17,18-dihydro-3,8,13,17-tetramethyl-, (17S-trans)-

Networked: 17 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Dube, Alok: 10 articles (06/2022 - 02/2004)
2.	Gupta, Pradeep Kumar: 4 articles (01/2014 - 11/2005)
3.	Sharma, Mrinalini: 4 articles (01/2014 - 02/2004)
4.	Bansal, Harsha: 3 articles (01/2014 - 02/2004)
5.	Sahu, Khageswar: 3 articles (01/2014 - 11/2005)
6.	Sarbadhikary, Paromita: 2 articles (11/2017 - 11/2017)
7.	Gupta, Pradeep K: 2 articles (06/2009 - 04/2006)
8.	Sharma, Sulbha: 2 articles (04/2006 - 01/2006)
9.	Feofanov, Alexei: 2 articles (02/2004 - 06/2002)
10.	Grichine, Alexei: 2 articles (02/2004 - 06/2002)

Related Diseases

1.	Mouth Neoplasms (Oral Cancer) 07/01/2023 - "We have explored the intracellular cell organelle's structural alterations after photodynamic treatment with chlorin p6 -histamine conjugate (Cp6 -his) in human oral cancer cells. " 11/01/2017 - "Iodinated chlorin p6 copper complex induces anti-proliferative effect in oral cancer cells through elevation of intracellular reactive oxygen species." 11/01/2017 - "In this study the anticancer cytotoxic efficacy of a new chlorophyll derivative, iodinated chlorin p6 copper complex (ICp6-Cu), combined with synchrotron X-ray radiation (8-10 keV) in two human oral cancer cell lines is explored. "
2.	Wounds and Injuries (Trauma) 02/01/2013 - "Topical photodynamic treatment with poly-L-lysine-chlorin p6 conjugate improves wound healing by reducing hyperinflammatory response in Pseudomonas aeruginosa-infected wounds of mice." 01/01/2014 - "The purpose of this work was to study the effect of poly-L-lysine-conjugated chlorin P6 (pl-cp6)-mediated antimicrobial photodynamic treatment (APDT) on collagen remodeling of murine excisional wounds infected with methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa (PAO). " 02/01/2013 - "We report the results of our investigations on the effect of antimicrobial photodynamic treatment (APDT) with poly-lysine-conjugated chlorin p6 (pl-cp6) on proinflammatory cytokine expression and wound healing in a murine excisional wound model infected with Pseudomonas aeruginosa. "
3.	Neoplasms (Cancer) 09/07/2016 - "We demonstrate in situ construction and characterization of supramolecular aggregates from chlorin p6 (Cp6) molecules in tumor cells. " 06/03/2009 - "These results suggest that the fluorescence imaging pattern of chlorin p6 could be useful in identifying the proliferating and differentiated population of cells in tumor tissue." 01/01/2006 - "We studied pharmacokinetics and tumor response to photodynamic therapy (PDT) using chlorin p6 (CP6) in hamster cheek pouch model. " 12/06/2017 - "Using chlorin p6, a chlorophyll derivative, we synthesized a novel iodinated chlorin p6-copper complex (ICp6-Cu) that can be applied to the photodynamic therapy and photon activation therapy of cancer. "
4.	Carcinoma (Carcinomatosis) 11/01/2005 - "Effect of varying extracellular pH on mode of cell death induced by photodynamic action of chlorin p6 was investigated in human colon carcinoma (Colo-205) cells. " 07/01/2023 - "Structural alterations in cell organelles induced by photodynamic treatment with chlorin p6 -histamine conjugate in human oral carcinoma cells probed by 3D fluorescence microscopy." 11/01/2017 - "Enhancement of radiosensitivity of oral carcinoma cells by iodinated chlorin p6 copper complex in combination with synchrotron X-ray radiation."
5.	Phototoxic Dermatitis (Phototoxicity) 04/01/2006 - "Irradiation with narrow bandwidth light showed that at low pH, the relative phototoxicity due to pp18 was higher than that due to chlorin p6. " 02/01/2004 - "In Colo-205 cells, the uptake and phototoxicity of chlorin p6 was observed to increase as the pH of the incubation medium decreased. "

Related Drugs and Biologics

1.	Copper
2.	Chlorophyll
3.	Lysine (L-Lysine)
4.	Collagen
5.	Photogem
6.	Reactive Oxygen Species (Oxygen Radicals)
7.	Cytokines
8.	Histamine (Histamine Dihydrochloride)
9.	lysyl chlorin p6
10.	1-phenyl-3,3-dimethyltriazene (PDT)

Related Therapies and Procedures

1.	Synchrotrons
2.	Photochemotherapy (Photodynamic Therapy)
3.	Therapeutics
4.	Lasers (Laser)