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A 771726

active metabolite of leflunomide; structure given in first source
Also Known As:
2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-butenamide; 2-hydroxyethylidene-cyanoacetic acid-4-trifluoromethyl anilide; A-771726; A77 1726; RS 61980
Networked: 28 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Williams, James W: 2 articles (04/2015 - 10/2014)
2. Soldano, Stefano: 2 articles (05/2009 - 01/2009)
3. Brizzolara, Renata: 2 articles (05/2009 - 01/2009)
4. Sulli, Alberto: 2 articles (05/2009 - 01/2009)
5. Montagna, Paola: 2 articles (05/2009 - 01/2009)
6. Cutolo, Maurizio: 2 articles (05/2009 - 01/2009)
7. Brouwers, J R B J: 2 articles (04/2005 - 09/2004)
8. van Roon, E N: 2 articles (04/2005 - 09/2004)
9. Yska, J P: 2 articles (04/2005 - 09/2004)
10. Samardzic, T: 2 articles (08/2002 - 01/2001)

Related Diseases

1. Rheumatoid Arthritis
2. Leukemia
3. Hyperalgesia
4. Type 1 Diabetes Mellitus (Autoimmune Diabetes)
5. Necrosis

Related Drugs and Biologics

1. leflunomide (Arava)
2. dihydroorotate dehydrogenase
3. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
4. Interleukins
5. Insulin Receptor Substrate Proteins
6. Interleukin 1 Receptor Antagonist Protein (Anakinra)
7. Ribosomal Protein S6
8. Vitamin K 3 (Menadione)
9. Cytochrome P-450 CYP1A2 (CYP1A2)
10. Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)

Related Therapies and Procedures

1. Transplantation (Transplant Recipients)