|1.||Bravo, Fernando J: 2 articles (02/2006 - 09/2003)|
|2.||Bernstein, David I: 2 articles (02/2006 - 09/2003)|
|3.||Schleiss, Mark R: 2 articles (01/2006 - 09/2003)|
|4.||McKenna, Charles E: 1 article (07/2008)|
|5.||Breitenbach, Julie M: 1 article (07/2008)|
|6.||Eriksson, Ulrika: 1 article (07/2008)|
|7.||Kim, Jae Seung: 1 article (07/2008)|
|8.||Borysko, Katherine Z: 1 article (07/2008)|
|9.||Hilfinger, John M: 1 article (07/2008)|
|10.||Peterson, Larryn W: 1 article (07/2008)|
08/01/2000 - "Cyclic HPMPC is safe and effective against systemic guinea pig cytomegalovirus infection in immune compromised animals."
08/01/2000 - "In efficacy studies in immune compromised guinea pigs challenged with a virulent salivary gland passaged guinea pig CMV, CHPMPC treatment significantly reduced mortality resulting from disseminated virus infection. "
02/15/2006 - "Treatment of the GPCMV-infected pregnant dam with 1 dose of cHPMPC improves the outcome of congenital infection and decreases viral replication in a guinea pig model."
02/15/2006 - "cHPMPC treatment did not prevent infection of the placenta or disseminated infection of the dam and pup but significantly decreased the amount of GPCMV in tissues. "
02/15/2006 - "Guinea pigs were monitored until delivery or were killed 10 days after infection, for the evaluation of the effect of cHPMPC on viral replication by polymerase chain reaction analysis in various dam and pup tissues. "
|2.||Herpesviridae Infections (Herpesvirus Infection)
07/01/2008 - "In gastrointestinal and liver homogenates, the cHPMPC prodrugs are rapidly hydrolyzed to 2. Prodrugs 3, 4, and 5 are nontoxic at 100 microM in HFF and KB cells and in cell-based plaque reduction assays had IC 50 values of 0.1-0.5 microM for HCMV and 10 microM for two orthopox viruses (vaccinia and cowpox). "
06/01/2003 - "Comparative effects of cidofovir and cyclic HPMPC on lethal cowpox and vaccinia virus respiratory infections in mice."
|4.||Cytomegalovirus Infections (Inclusion Disease)
|2.||cyclic- 1- (3- hydroxy- 2- phosphonylmethoxypropyl)cytosine
|6.||9- (3- hydroxy- 2- phosphonylmethoxypropyl)adenine