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BN 52205
a synthetic aza alkyl lysophospholipid of MW 436; structure given in first source
Also Known As:
3-methoxy-2-N,N-methyloctadecylaminopropyloxyphosphorylcholine; BN-52205; 3,5-Dioxa-8-aza-4-phosphahexacosan-1-aminium, 4-hydroxy-7-(methoxymethyl)-N,N,N,8-tetramethyl-, hydroxide, inner salt, 4-oxide
Networked:
3
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Lipids: 114793
Membrane Lipids: 1591
Phospholipids: 11903
Glycerophosphates: 118
Phosphatidic Acids: 358
Lysophospholipids: 554
BN 52205: 3
Related Diseases
1.
Neoplasms (Cancer)
01/01/1994 - "
The study of the degree of differential growth inhibition has shown a statistically significant differential cell sensitivity for BN 52205 and BN 52211 for colon and melanoma tumor cells.
"
11/01/1991 - "
The anti-tumor cytotoxic activity of four newly synthesized aza alkyl lysophospholipids (AALP), namely BN 52205, BN 52207, BN 52208 and BN 52211, was investigated.
"
2.
Melanoma (Melanoma, Malignant)
01/01/1994 - "
The study of the degree of differential growth inhibition has shown a statistically significant differential cell sensitivity for BN 52205 and BN 52211 for colon and melanoma tumor cells.
"
3.
Colonic Neoplasms (Colon Cancer)
01/01/1994 - "
We have characterized the cytostatic activity of four ether phospholipids, the methoxy-substituted edelfosine (ET-18-OCH 3), the thio-derivative ilmofosine (BM 41.440), and two new aza-alkylphospholipids, BN 52205 and BN 52211, on a human tumor cell line derived from a colon adenocarcinoma, the HT29.
"
Related Drugs and Biologics
1.
BN 52211
2.
Cytostatic Agents
3.
Phospholipid Ethers
4.
Lysophospholipids
5.
BN 52208
6.
BN 52207
7.
ilmofosine
8.
edelfosine