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neokestose

sugar found in vegetables; structure given in first source

Networked: 2 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Polysaccharides: 15383
  - Oligosaccharides: 3566
    - Trisaccharides: 123
      - neokestose: 2

Experts

1.	Chang, Jan-Yi: 2 articles (07/2017 - 07/2015)
2.	Lee, Shun-Mei: 2 articles (07/2017 - 07/2015)
3.	Sheu, Dey-Chyi: 2 articles (07/2017 - 07/2015)
4.	Wu, Jiann-Shing: 2 articles (07/2017 - 07/2015)
5.	Chen, C Will: 1 article (07/2017)
6.	Lin, Ming-Tse: 1 article (07/2017)

Related Diseases

1.	Colorectal Neoplasms (Colorectal Cancer) 07/01/2015 - "In the present study, the effects of neokestose on cell proliferation, cell cycle and apoptosis of the colorectal cancer cell line Caco-2 were investigated to evaluate its anti-cancer effect. " 07/01/2015 - "Accordingly, the present study provided in vitro evidence that neokestose may be used as a dietary chemopreventive agent, whose application is more rational than that of COX-2 inhibitors or aspirin for preventing colorectal cancer." 07/01/2015 - "Western blot analysis showed that the overexpression of nuclear factor-κB, a central molecule responsible for the transition from inflammation to cancer, and cyclooxygenase-2, an important enzyme in colorectal tumorigenesis, in colorectal carcinoma cells was inhibited by neokestose. "
2.	Neoplasms (Cancer) 07/01/2015 - "In the present study, the effects of neokestose on cell proliferation, cell cycle and apoptosis of the colorectal cancer cell line Caco-2 were investigated to evaluate its anti-cancer effect. " 07/01/2015 - "Western blot analysis showed that the overexpression of nuclear factor-κB, a central molecule responsible for the transition from inflammation to cancer, and cyclooxygenase-2, an important enzyme in colorectal tumorigenesis, in colorectal carcinoma cells was inhibited by neokestose. "
3.	Melanoma (Melanoma, Malignant) 07/01/2017 - "The present study aimed to determine whether neokestose may suppress growth of the A2058 melanoma cell line. " 07/01/2017 - "The present findings support the requirement for further investigation into the potential use of neokestose as an additional or chemopreventive therapeutic agent for the treatment of melanoma." 07/01/2017 - "These findings suggest that neokestose treatment may induce suppression of A2058 melanoma cell viability via inhibition of the NF‑κB pathway. " 07/01/2017 - "Neokestose suppresses the growth of human melanoma A2058 cells via inhibition of the nuclear factor‑κB signaling pathway."
4.	Carcinogenesis 07/01/2015 - "Western blot analysis showed that the overexpression of nuclear factor-κB, a central molecule responsible for the transition from inflammation to cancer, and cyclooxygenase-2, an important enzyme in colorectal tumorigenesis, in colorectal carcinoma cells was inhibited by neokestose. "
5.	Inflammation (Inflammations) 07/01/2015 - "Western blot analysis showed that the overexpression of nuclear factor-κB, a central molecule responsible for the transition from inflammation to cancer, and cyclooxygenase-2, an important enzyme in colorectal tumorigenesis, in colorectal carcinoma cells was inhibited by neokestose. "

Related Drugs and Biologics

1.	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)
2.	Aspirin (Acetylsalicylic Acid)
3.	Cyclooxygenase 2 (Cyclooxygenase-2)
4.	Enzymes