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heme polymerase
malarial enzyme forms haemozoin from heme derived from hemoglobin; no information on mechanism 2/92
Also Known As:
haem polymerase
Networked:
7
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Enzymes and Coenzymes: 1
Enzymes: 152586
Transferases: 6589
heme polymerase: 7
Related Diseases
1.
Malaria
02/01/1993 - "
The proposal that this inhibition of heme polymerase can explain the specific toxicity of these drugs for the intraerythrocytic malaria parasite is then developed by showing that it is consistent with much of the disparate information currently available.
"
07/01/1996 - "
Haemozoin formation in malaria parasites: is there a haem polymerase?
"
08/31/1993 - "
To evaluate the response of heme polymerase to treatment of malaria with chloroquine, we used mice infected with Plasmodium berghei.
"
01/01/1992 - "
Heme polymerase: modulation by chloroquine treatment of a rodent malaria.
"
01/09/1992 - "
Inhibition by chloroquine of a novel haem polymerase enzyme activity in malaria trophozoites.
"
2.
Body Weight (Weight, Body)
11/01/1997 - "
Six hours after treatment of these mice with 3 micromol of chloroquine per 25 g of body weight, there were significant losses of heme polymerase I (HPA I).
"
Related Drugs and Biologics
1.
Chloroquine (Aralen)
2.
hemozoin
3.
Sodium Acetate (Sodium Acetate, Anhydrous)
4.
Hemoglobins (Hemoglobin)
5.
Hemin (Panhematin)
6.
Enzymes
7.
polyacrylamide
Related Therapies and Procedures
1.
Aftercare (After-Treatment)