|1.||Sheppard, Dean: 7 articles (07/2010 - 03/2003)|
|2.||Violette, Shelia M: 6 articles (12/2008 - 01/2007)|
|3.||Weinreb, Paul H: 6 articles (12/2008 - 01/2007)|
|4.||Ramos, Daniel M: 5 articles (01/2009 - 06/2002)|
|5.||Dang, Dongmin: 4 articles (01/2009 - 10/2003)|
|6.||Horan, Gerald S: 4 articles (01/2008 - 01/2007)|
|7.||Häkkinen, Lari: 3 articles (06/2009 - 05/2008)|
|8.||Dolinski, Brian M: 3 articles (12/2008 - 01/2007)|
|9.||Gardner, Humphrey A: 3 articles (12/2008 - 01/2007)|
|10.||Thomas, Gareth J: 3 articles (10/2008 - 12/2007)|
07/01/2010 - "We conclude that absence of the beta6 integrin subunit protects the infant murine lung against IL-1beta-induced inflammation and injury."
10/01/1998 - "Inactivation of the integrin beta6 subunit gene in mice resulted in an unexpected phenotype-functionally significant inflammation of the skin and lungs. "
10/01/1998 - "These findings suggested a role for ligation of the alphav beta6 integrin on epithelial cells in downregulating epithelial inflammation. "
05/01/2008 - "Remarkably, integrin beta6 knockout mice developed classic signs of spontaneous, chronic periodontal disease with characteristic inflammation, epithelial down-growth, pocket formation, and bone loss around the teeth. "
01/01/2007 - "Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse."
|2.||Pulmonary Fibrosis (Hamman Rich Syndrome)
02/15/2000 - "We then compared the gene expression patterns in these mice with 129 mice carrying a null mutation in the epithelial-restricted integrin beta6 subunit (beta6(-/-)), which develop inflammation but are protected from pulmonary fibrosis. "
01/01/2008 - "Partial inhibition of TGF-beta using alpha(v)beta6 integrin antibodies is effective in blocking murine pulmonary fibrosis without exacerbating inflammation. "
|3.||Squamous Cell Carcinoma (Epidermoid Carcinoma)
10/24/2003 - "The purpose of the present study was to determine whether integrin beta6 signaling activates Fyn and thus promotes oral squamous cell carcinoma progression. "
07/01/2007 - "Overexpression of the alpha v beta 6 integrin in cervical squamous cell carcinoma is a prognostic factor for decreased survival."
10/01/2005 - "Alpha v beta 6 integrin down-regulates the MMP-13 expression in oral squamous cell carcinoma cells."
11/02/2001 - "Role of the alpha(v)beta6 integrin in human oral squamous cell carcinoma growth in vivo and in vitro."
04/09/2004 - "The integrin beta6 has been shown to promote invasion and experimental metastasis by oral squamous cell carcinoma (SCC). "
10/01/2008 - "The successful preparation of rabbit anti pig beta6LBD polyclonal antibody with high affinity and specificity will lay a foundation for further research into the function of integrin beta6 in FMDV infection."
06/01/2000 - "In this report, we show that human colon carcinoma cells (SW480) that are normally nonpermissive for FMDV become susceptible to infection as a result of transfection with the integrin beta6 subunit and expression of alphavbeta6 at the cell surface. "
09/01/2007 - "In order to study the roles of integrin beta6 in Foot-and-Mouth Disease Virus infection, pig integrin beta6 was firstly molecularly cloned from RNA of the tongue and lung of recovered pig infected experimentally with foot-and-mouth-disease virus (FMDV), and was compared with the beta6 gene of other animals available in GenBank at nucleotide and amino acid leves. "
04/01/2010 - "The small interfering RNA (siRNA) silencing of integrin beta6 subunit inhibited virus proliferation, confirming that alphaVbeta6 mediates the CAV9 infection. "
|5.||Wounds and Injuries (Trauma)
06/01/2009 - "Similar to human wounds, the expression of beta6 integrin was induced in the pig wounds 7 days after wounding and remained upregulated >49 days. "
06/01/2009 - "In this study, expression of beta6 integrin and members of the TGF-beta pathway were studied in experimental wounds of human gingiva and both gingiva and skin of red Duroc pigs using real-time PCR, gene microarrays, and immunostaining. "
06/01/2009 - "Significantly higher expression levels of beta6 integrin and TGF-beta1 were observed in the pig gingival wounds compared with skin. "
05/01/2009 - "Mice lacking beta6 integrin in skin show accelerated wound repair in dexamethasone impaired wound healing model."
|1.||Transforming Growth Factor beta (TGF-beta)
|4.||RNA (Ribonucleic Acid)
|5.||Transforming Growth Factor beta1 (TGF beta 1)
|6.||Proteins (Proteins, Gene)
|7.||Matrix Metalloproteinase 9 (Gelatinase B)
|8.||Messenger RNA (mRNA)