BRL 44408

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2 relevant articles (0 outcomes, 0 trials/studies) found for this Bio-Agent

Description: has selectivity for adrenergic alpha-2A receptors; BRL 48962 is the R-enantiomer; BRL 48553 is the R-enantiomer

Also Known As:

1H-Isoindole, 2-((4,5-dihydro-1H-imidazol-2-yl)methyl)-2,3-dihydro-1-methyl-; 2-((4,5-dihydro-1H-imidazol-2-yl)methyl)-2,3-dihydro-1-methyl-1H-isoindole; BRL 48553; BRL 48962; BRL-44408; BRL-48553; BRL-48962

Bio-Agent Context: Research Results

Heterocyclic Compounds: 23

1-Ring Heterocyclic Compounds

Azoles: 224

Imidazoles: 94

BRL 44408: 2

2-Ring Heterocyclic Compounds

Isoindoles

BRL 44408: 2

Related Diseases

1.	Pain (Aches) 11/01/2007 - "BACKGROUND: We studied whether peripheral alpha2-adrenergic receptors are involved in the antihyperalgesic effects of oxcarbazepine by examining the effects of yohimbine (selective alpha2-adrenoceptor antagonist), BRL 44408 (selective alpha(2A)-adrenoceptor antagonist), MK-912 (selective alpha2C-adrenoceptor antagonist), and clonidine (alpha2-adrenoceptor agonist) on the antihyperalgesic effect of oxcarbazepine in the rat model of inflammatory pain" Get all the results and reference details, order at left...
2.	Hypothermia 09/01/2005 - "In WT mice, following the alpha(2A)-adrenoceptor antagonist 2-((4,5-dihydro-1H-imidazol-2-yl)methyl)-2,3-dihydro-1-methyl-1H-isoindole (1 mg kg(-1), s.c.), MDMA (20 mg kg(-1)) produced an initial hypothermia" Get all the results and reference details, order at left...
2 Diseases and 2 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	N-Methyl-3,4-methylenedioxyamphetamine (MDMA)
2.	Yohimbine (Yocon)
3.	Clonidine (ST 155)
4.	L 657743
5.	oxcarbazepine (Trileptal)
5 Drugs and Important Bio-Agents and 2 more articles analyzed in the Research Interface, order at left...

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