BPDE-III

Also Known As:

9r,10t-dihydroxy-7c,8c-oxy-7,8,9,10-tetrahydrobenzeno(a)pyrene; benzo(a)pyrene diolepoxide III

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Carcinogenesis 03/15/1994 - "A metabolite of benzo[a]pyrene, 9-r,10-t-dihydroxy-7,8-c-oxy-7,8,9,10- tetrahydrobenzo[a]pyrene (BPDE-III), that is not thought to be involved in carcinogenesis has nevertheless been shown to bind extensively to DNA in vitro. "
2.	DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes) 12/01/1991 - "By comparison of the D0's, the DNA-repair-deficient cell lines were found to be 4-5-fold more sensitive to the killing effects of BPDE-III than were the repair-proficient AT3-2 cells."