|1.||Lan, Q: 5 articles (04/2010 - 02/2003)|
|2.||Lan, Que: 4 articles (01/2012 - 06/2009)|
|3.||Vyazunova, I: 3 articles (04/2010 - 06/2005)|
|4.||Ferdinandusse, S: 3 articles (06/2006 - 03/2000)|
|5.||Denis, S: 3 articles (06/2006 - 03/2000)|
|6.||Peng, Rong: 2 articles (01/2012 - 01/2011)|
|7.||Dyer, David H: 2 articles (09/2010 - 06/2009)|
|8.||Wanders, R J: 2 articles (12/2001 - 03/2000)|
|9.||Molesini, Barbara: 1 article (07/2013)|
|10.||Pandolfini, Tiziana: 1 article (07/2013)|
01/01/2011 - "In vivo functional genomic studies of sterol carrier protein-2 gene in the yellow fever mosquito."
09/07/2010 - "In this study, we used site-directed mutagenesis to investigate the ligand selectivity and in vivo function of the yellow fever mosquito sterol carrier protein-2 protein (AeSCP-2). "
06/01/2005 - "The effect of gene expression knockdown was used to study the function of the sterol carrier protein-2 (AeSCP-2) in the yellow fever mosquito, Aedes aegypti. "
01/01/2012 - "THAP and ATF-2 regulated sterol carrier protein-2 promoter activities in the larval midgut of the yellow fever mosquito, Aedes aegypti."
04/01/2010 - "Yellow fever mosquito sterol carrier protein-2 gene structure and transcriptional regulation."
|2.||Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked)
06/01/2004 - "Additional studies in fibroblasts from patients with X-linked adrenoleukodystrophy, straight-chain acyl-CoA oxidase (SCOX) deficiency, d-bifunctional protein (DBP) deficiency, and rhizomelic chondrodysplasia punctata type 1, together with direct enzyme measurements with human recombinant l-bifunctional protein (LBP) and DBP expressed in a fox2 deletion mutant of Saccharomyces cerevisiae, show that the main enzymes involved in beta-oxidation of C16DCA are SCOX, both LBP and DBP, and sterol carrier protein X, possibly together with the classic 3-ketoacyl-CoA thiolase. "
12/01/2001 - "By making use of fibroblasts from patients with defined mitochondrial and peroxisomal fatty acid oxidation defects, we show in this article that peroxisomes, and not mitochondria, are involved in DHA formation by catalyzing the beta-oxidation of C24:6n-3 to C22:6n-3. Additional studies of fibroblasts from patients with X-linked adrenoleukodystrophy, straight-chain acyl-CoA oxidase (SCOX) deficiency, d-bifunctional protein (DBP) deficiency, and rhizomelic chondrodysplasia punctata type 1, and of fibroblasts from l-bifunctional protein and sterol carrier protein X (SCPx) knockout mice, show that the main enzymes involved in beta-oxidation of C24:6n-3 to C22:6n-3 are SCOX, DBP, and both 3-ketoacyl-CoA thiolase and SCPx. "
|3.||Cardiac Sudden Death (Sudden Cardiac Arrest)
11/01/2004 - "Phytanic acid accumulation is associated with conduction delay and sudden cardiac death in sterol carrier protein-2/sterol carrier protein-x deficient mice."
11/01/2004 - "We show in this study that mice deficient in SCP2 and SCPx (SCP2null) develop a cardiac phenotype leading to a high sudden cardiac death rate if mice are maintained on diets enriched for phytol (a metabolic precursor of branched-chain fatty acids). "
|4.||Zellweger Syndrome (Zellweger's Syndrome)
03/01/2000 - "We found that SCPx is not only stable in the cytosol, but displays a higher activity in fibroblasts from patients with Zellweger syndrome than in control fibroblasts. "
03/01/2000 - "In addition to SCPx activity measurements in fibroblasts from patients with a defect in peroxisomal beta-oxidation of unresolved etiology, we studied the stability and activity of SCPx in fibroblasts from patients with Zellweger syndrome, which lack functional peroxisomes. "
04/01/1994 - "Previous work has established that the absence of peroxisomes, as occurs in Zellweger syndrome, is accompanied by the absence of cellular sterol carrier protein-2 (SCP2). "
08/11/1995 - "To assess the possibility that sterol carrier protein-2 (SCP-2) is involved in this transport, we studied the time course of newly synthesized cholesterol incorporation in the plasma membrane of normal and SCP-2-deficient (Zellweger syndrome) human fibroblasts. "
|5.||Hepatocellular Carcinoma (Hepatoma)
03/01/1991 - "Elevated cholesterol and decreased sterol carrier protein-2 in peroxisomes from AS-30D hepatoma compared to normal rat liver."
02/01/2008 - "Treating with the fatty acid, lauric acid, induced SCPx mRNA levels in rat liver and in rat hepatoma H4IIE cells but enhanced protein levels of SCPx and the thiolase produced as a post-translational modification of SCPx were only seen in H4IIE cells. "
|1.||sterol carrier proteins
|4.||type 1 Rhizomelic chondrodysplasia punctata
|6.||Fatty Acids (Saturated Fatty Acids)
|8.||Messenger RNA (mRNA)