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half protocol

chemotherapy protocol consisting of above cpds with allopurinol protection; used in treatment of advanced gastrointestinal & breast cancer

Also Known As:

half regimen

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Therapy Context: Research Results

Therapeutics: 1158551
- Drug Therapy: 293145
  - Combination Drug Therapy: 12066
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - half protocol: 2
  - Antineoplastic Protocols: 55
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - half protocol: 2
- Clinical Protocols
  - Antineoplastic Protocols: 55
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - half protocol: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidinones: 71
      - Uracil: 1493
        Fluorouracil: 26711
        half protocol: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Pteridines: 147
      - Pterins: 160
        Folic Acid: 19425
        Tetrahydrofolates: 8
        Formyltetrahydrofolates
        Leucovorin: 5743
        half protocol: 2
Enzymes and Coenzymes: 1
- Coenzymes: 558
  - Tetrahydrofolates: 8
    - Formyltetrahydrofolates
      - Leucovorin: 5743
        half protocol: 2
Organic Chemicals: 133
- Amides: 2428
  - Urea: 15015
    - Hydroxyurea: 3694
      - half protocol: 2

Experts

1.	Chan, Edwin C H: 1 article (07/2021)
2.	Fong, Daniel T P: 1 article (07/2021)
3.	Sun, Wei: 1 article (07/2021)

Related Diseases

1.	Carcinoma (Carcinomatosis) 12/01/1991 - "Twenty patients with advanced carcinomas of the colorectum, pancreas, stomach, and breast were enrolled in a Phase I study of a sequential administration of 5-fluorouracil-leucovorin (FU-LV) combination followed by hydroxyurea (HU) with allopurinol protection (HALF regimen). "
2.	Ankle Injuries (Ankle Injury) 07/01/2021 - "The risk of ankle sprain could increase in the latter minutes in each half protocol. "

Related Drugs and Biologics

1.	Hydroxyurea (Hydrea)
2.	Allopurinol (Remid)