sulfosuccinimidyl 4- (N- maleimidomethyl)cyclohexane- 1- carboxylate

Also Known As:

sulfo-SMCC

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Dicarboxylic Acids: 108
      - Maleates: 3
        Maleimides: 16
        sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate: 6
- Imides: 79
  - Maleimides: 16
    - sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate: 6
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrroles: 369
      - Maleimides: 16
        sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate: 6

Experts

1.	Xia, Chang-Qing: 2 articles (12/2015 - 01/2015)
2.	Becker, María Inés: 1 article (04/2018)
3.	Del Campo, Miguel: 1 article (04/2018)
4.	López, Mercedes N: 1 article (04/2018)
5.	Palacios, Miriam: 1 article (04/2018)
6.	Salazar-Onfray, Flavio: 1 article (04/2018)
7.	Tampe, Ricardo: 1 article (04/2018)
8.	Zhong, Ta-Ying: 1 article (04/2018)
9.	Concepción, Juan Luis: 1 article (06/2016)
10.	Cáceres, Ana J: 1 article (06/2016)

Related Diseases

1.	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/01/2015 - "In this study, we have evaluated our recently developed method for antigen-cell coupling using sulfosuccinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate (sulfo-SMCC) heterobifunctional crosslinker in prevention and reversal of experimental autoimmune encephalomyelitis (EAE). "
2.	Neuroectodermal Tumors (Neuroectodermal Tumor) 04/25/2018 - "Here, we evaluated the carrier and antitumor activity of novel hemocyanins with documented immunogenicity obtained from Concholepas concholepas (CCH) and Fissurella latimarginata (FLH), coupled through sulfo-SMCC to P10, a mimetic peptide of GD2, the major ganglioside constituent of neuroectodermal tumors, and incorporating AddaVax as an adjuvant. "
3.	Wounds and Injuries (Trauma) 03/01/2011 - "We conclude that collagen scaffolds chemically conjugated to VEGF by Traut's reagent and sulfo-SMCC is an effective delivery system in wound repair and tissue engineering."
4.	Neoplasms (Cancer) 07/01/1997 - "For pretargeting tumor, streptavidin-monoclonal antibody (StAv-mab) conjugates were prepared by cross-linking sulfo-SMCC-derivatized streptavidin to a free thiol (SH) group on MN-14 [a high-affinity anti-carcinoembryonic antigen (CEA) mab]. "
5.	Melanoma (Melanoma, Malignant) 12/04/2015 - "Here we designed a strategy to enhance antigen-specific immune response via administering sulfosuccinimidyl-4-[N-maleimidomethyl] cyclohexane-1-carboxylate (sulfo-SMCC)-conjugated melanoma tumor antigen GP10025-33 peptide-coupled syngeneic spleen cells in a mouse model of melanoma. "

Related Drugs and Biologics

1.	Antigens
2.	Cyclohexane
3.	Peptides (Polypeptides)
4.	Indicators and Reagents (Reagents)
5.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
6.	Streptavidin
7.	Sulfhydryl Compounds (Thiols)
8.	Hemocyanins
9.	Gangliosides
10.	Collagen