bassic acid

from Bemelia sartorum; RN given refers to (2beta,3beta,4alpha)-isomer; RN for cpd without isomeric designation not avail 12/91

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Visceral Leishmaniasis (Kala Azar) 05/01/2006 - "The in vitro antileishmanial activity of bassic acid being encouraging, its activity in vivo was evaluated in hamster models of visceral leishmaniasis, both in free form, as well as incorporated in two different delivery systems, viz microemulsions and polylactide nanoparticles. "
2.	Leishmaniasis 05/01/2006 - "Critical evaluation of the therapeutic potential of bassic acid incorporated in oil-in-water microemulsions and poly-D,L-lactide nanoparticles against experimental leishmaniasis."
3.	Hypoglycemia (Reactive Hypoglycemia) 05/01/1991 - "It is suggested that the hypoglycemia activity of bassic acid may be mediated through enhanced secretion of insulin from the pancreatic beta-cells."
4.	Body Weight (Weight, Body) 05/01/2006 - "At an equivalent dose of 2 mg kg(-1) body weight, when injected subcutaneously for a total of six doses in 15 days, bassic acid was found to reduce spleen parasite loads by 45, 62 and 78% in free, microemulsion-incorporated and nanoparticle-incorporated forms, respectively. "

1.	Insulin (Novolin)
2.	poly(lactide) (polylactic acid)