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edobacomab

monoclonal IgM antibody against endotoxin

Also Known As:

E5 monoclonal antibody; Xomen; Xomen-E5

Networked: 3 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Monoclonal Antibodies: 56412
        edobacomab: 3
    - Immunoproteins: 43
      - Immunoglobulins: 30480
        Antibodies: 133716
        Monoclonal Antibodies: 56412
        edobacomab: 3
  - Globulins: 3062
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Monoclonal Antibodies: 56412
        edobacomab: 3

Related Diseases

1.	Sepsis (Septicemia) 01/01/1994 - "[Phase II study of edobacomab (E5) in the treatment of gram-negative sepsis]." 01/01/1994 - "[Phase I study of edobacomab (E5) in patients with gram-negative sepsis]." 01/01/1994 - "A clinical Phase I study of E5, edobacomab, an anti-endotoxin monoclonal IgM antibody was carried out to evaluate its efficacy, safety and pharmacokinetics and in parallel, explore an optimum dosage in the treatment of patients with gram-negative sepsis (incl. " 11/01/1990 - "These techniques have been applied in clinical trials assessing E5 monoclonal antibody therapy in patients with gram-negative sepsis and in others evaluating the use of imipenem versus tobramycin and clindamycin in the treatment of intraabdominal infection. "
2.	Intraabdominal Infections 11/01/1990 - "These techniques have been applied in clinical trials assessing E5 monoclonal antibody therapy in patients with gram-negative sepsis and in others evaluating the use of imipenem versus tobramycin and clindamycin in the treatment of intraabdominal infection. "

Related Drugs and Biologics

1.	Imipenem
2.	Tobramycin (Nebcin)
3.	Immunoglobulin M (IgM)
4.	Endotoxins
5.	Clindamycin (Cleocin)

Related Therapies and Procedures

1.	Therapeutics