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Bodipy-verapamil

structure given in first source; substrate for P glycoprotein in MDR cells

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Ethylamines: 5
    - Phenethylamines: 28
      - Verapamil: 6163
        Bodipy-verapamil: 3

Experts

1.	Booth-Genthe, Catherine L: 1 article (08/2011)
2.	Gupta, Anshul: 1 article (08/2011)
3.	Harris, Jennifer: 1 article (08/2011)
4.	Unadkat, Jashvant D: 1 article (08/2011)
5.	Zolnerciks, Joseph K: 1 article (08/2011)

Related Diseases

1.	Lewis Lung Carcinoma 08/01/2011 - "We have used a sensitive flow cytometry assay to measure the ability of various drugs to inhibit the initial rate of accumulation of two fluorescent drug analogs (probe substrates), 4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s -indacene (BODIPY)-verapamil and BODIPY-prazosin, into Lewis lung carcinoma-porcine kidney 1 (LLC-PK1) cells expressing human or rat P-gp. "
2.	Neoplasms (Cancer) 07/17/1995 - "After interaction with resistant cancer cells, the antibodies induced an average 50% increase in cellular accumulation of doxorubicin and Bodipy-verapamil. "
3.	Cysts 07/06/1995 - "Bodipy-verapamil is accumulated within the cyst lumen showing that epithelial P-glycoprotein function may be used to target substrates to renal cysts."

Related Drugs and Biologics

1.	Member 1 Subfamily B ATP Binding Cassette Transporter
2.	Prazosin (Minipress)
3.	Doxorubicin (Adriamycin)
4.	Antibodies
5.	4,4- difluoro- 4- bora- 3a,4a- diaza- s- indacene (BODIPY)