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SC 37698

reduces development & progression of monocrotaline pulmonary hypertension; analogue of SC 39026

Also Known As:

SC-37698

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzoates: 426
        Chlorobenzoates
        SC 37698: 1
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Benzoates: 426
      - Chlorobenzoates
        SC 37698: 1

Related Diseases

1.	Hypertrophy 10/01/1991 - "In the hilar pulmonary arteries assessed at 3 wk only, SC-37698 significantly decreased monocrotaline-induced endothelial injury, subendothelial edema, migration of smooth muscle cells into subendothelium, medial hypertrophy, collagen accumulation, and abnormal distribution of elastin as interlamellar islands. "
2.	Pulmonary Hypertension 10/01/1991 - "Thus infusion of SC-37698 reduces monocrotaline-induced pulmonary hypertension when administered before or even after development of early vascular changes." 10/01/1991 - "Inhibition of elastolysis by SC-37698 reduces development and progression of monocrotaline pulmonary hypertension."
3.	Edema (Dropsy) 10/01/1991 - "In the hilar pulmonary arteries assessed at 3 wk only, SC-37698 significantly decreased monocrotaline-induced endothelial injury, subendothelial edema, migration of smooth muscle cells into subendothelium, medial hypertrophy, collagen accumulation, and abnormal distribution of elastin as interlamellar islands. "

Related Drugs and Biologics

1.	Monocrotaline
2.	Elastin
3.	Collagen