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SK&F 106760

RN & structure given in first source; glycoprotein IIb/IIIa antagonist

Also Known As:

Ac-cyclo-S,S-(Cys-(N(alpha)-Me)Arg-Gly-Asp-Pen)-NH2; SK&F-106760; SKF 106760

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - SK&F 106760: 2
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - SK&F 106760: 2

Related Diseases

1.	Thrombosis (Thrombus) 08/01/1994 - "In anesthetized dogs, SK&F 106760 (0.3-3.0 mg/kg i.v.) produced a complete inhibition of platelet-dependent coronary artery thrombosis, with a dose-related duration of action.(ABSTRACT TRUNCATED AT 250 WORDS)" 05/01/1992 - "In this model, the administration of 1 mg/kg i.v. SK&F 106760 prevented thrombosis of the stenotic carotid artery. " 05/01/1992 - "Both spontaneous and evoked (increased carotid stenosis) aspirin-resistant thrombosis were abolished by SK&F 106760 treatment. "
2.	Carotid Stenosis (Carotid Artery Stenosis) 05/01/1992 - "Both spontaneous and evoked (increased carotid stenosis) aspirin-resistant thrombosis were abolished by SK&F 106760 treatment. "
3.	Pathologic Constriction (Stenosis) 05/01/1992 - "In addition, the antithrombotic effects of SK&F 106760 were compared with those of aspirin in an acute canine model of extracranial carotid artery thrombosis with high-grade stenosis. "
4.	Carotid Artery Thrombosis 05/01/1992 - "In addition, the antithrombotic effects of SK&F 106760 were compared with those of aspirin in an acute canine model of extracranial carotid artery thrombosis with high-grade stenosis. "

Related Drugs and Biologics

1.	Aspirin (Acetylsalicylic Acid)