D-lactate dehydrogenase

catalyzes the conversion of (R)-lactate & NAD+ to pyruvate & NADH; in human, the protein encoded by this gene belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family; RefSeq NM_194436 (human); NM_027570 (mouse)

Also Known As:

B2133 protein, E coli; D-lactate dehydrogenase (NAD); D-lactate dehydrogenase, E coli; D-lactate dehydrogenase, mouse; DLD protein, E coli; LDHD protein, human; Ldhd protein, mouse; lactate dehydrogenase D, human; lactate dehydrogenase D, mouse

Networked: 9 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Oxidoreductases: 13671
    - Alcohol Oxidoreductases: 56
      - Lactate Dehydrogenases: 61
        D-lactate dehydrogenase: 9

Experts

1.	Chan, Godfrey Chi Fung: 1 article (07/2021)
2.	Fung, Cheuk-Wing: 1 article (07/2021)
3.	Kwong, Anna Ka-Yee: 1 article (07/2021)
4.	Rodenburg, Richard J T: 1 article (07/2021)
5.	Smeitink, Jan: 1 article (07/2021)
6.	Wong, Sheila Suet-Na: 1 article (07/2021)
7.	Berriman, M: 1 article (12/2019)
8.	Blackburn, G: 1 article (12/2019)
9.	Carter, K C: 1 article (12/2019)
10.	Coombs, G H: 1 article (12/2019)

Related Diseases

1.	Hyperuricemia 12/02/2019 - "Hyperuricemia and gout caused by missense mutation in d-lactate dehydrogenase."
2.	Cytochrome-c Oxidase Deficiency 07/01/2021 - "Human d-lactate dehydrogenase deficiency by LDHD mutation in a patient with neurological manifestations and mitochondrial complex IV deficiency."
3.	Prostatic Neoplasms (Prostate Cancer) 03/01/2013 - "Prostate cancer cells metabolize d-lactate inside mitochondria via a D-lactate dehydrogenase which is more active and highly expressed than in normal cells."
4.	Neurologic Manifestations (Neurological Manifestations) 07/01/2021 - "Human d-lactate dehydrogenase deficiency by LDHD mutation in a patient with neurological manifestations and mitochondrial complex IV deficiency."
5.	Infections 10/01/2017 - "The D-lactate dehydrogenase MoDLD1 is essential for growth and infection-related development in Magnaporthe oryzae."

Related Drugs and Biologics

1.	Lactic Acid (Lactate)
2.	Enzymes
3.	DNA (Deoxyribonucleic Acid)
4.	branched-chain-amino-acid transaminase