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serine(71)- interleukin-1 beta (OCT 43)
recombinant human interleukin-1 beta analogue; Cys replaced by Ser at position 71; regulator of hematopoiesis in patients receiving chemotherapy for urogenital cancers
Also Known As:
OCT 43
; interleukin-1 beta, serine(71)-; 71-Ser-IL-1 beta; IL-1 beta, Ser(71)-; OCT-43
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Proteins: 484843
Intercellular Signaling Peptides and Proteins: 29768
Cytokines: 164289
Interleukins: 25257
Interleukin-1: 10822
Interleukin-1beta: 7335
serine(71)- interleukin-1 beta: 2
Monokines: 214
Interleukin-1: 10822
Interleukin-1beta: 7335
serine(71)- interleukin-1 beta: 2
Recombinant Proteins: 2754
serine(71)- interleukin-1 beta: 2
Peptides: 82426
Intercellular Signaling Peptides and Proteins: 29768
Cytokines: 164289
Interleukins: 25257
Interleukin-1: 10822
Interleukin-1beta: 7335
serine(71)- interleukin-1 beta: 2
Monokines: 214
Interleukin-1: 10822
Interleukin-1beta: 7335
serine(71)- interleukin-1 beta: 2
Biological Factors: 2472
Intercellular Signaling Peptides and Proteins: 29768
Cytokines: 164289
Interleukins: 25257
Interleukin-1: 10822
Interleukin-1beta: 7335
serine(71)- interleukin-1 beta: 2
Monokines: 214
Interleukin-1: 10822
Interleukin-1beta: 7335
serine(71)- interleukin-1 beta: 2
Related Diseases
1.
Chills
10/01/1991 - "
Adverse effects associated with OCT-43 injections were high fever and chills, but they were controlled by indomethacin.
"
2.
Neutropenia
10/01/1991 - "
Fifty thousand units of recombinant human interleukin-1 (IL-1) beta analogue OCT-43 (Otsuka Pharmaceutical Co., Ltd., Tokyo, Japan) was administered subcutaneously only once or twice when severe neutropenia (less than 500/microliters) continued for 2 consecutive days.
"
3.
Glioma (Gliomas)
09/01/1994 - "
Five glioma cell lines, U-251 MG, U-373 MG, U-87 MG, A-172, and T98G, were incubated in medium containing 1% fetal calf serum and various concentrations of different type of rHuIL-1: OCT-43 (rHuIL-1 beta), OCT-7000 (rHuIL-1 alpha), and OCT-8000 (rHuIL-1 alpha).
"
4.
Fever (Fevers)
10/01/1991 - "
Adverse effects associated with OCT-43 injections were high fever and chills, but they were controlled by indomethacin.
"
Related Drugs and Biologics
1.
Bovine Serum Albumin
2.
Interleukin-1 (Interleukin 1)
3.
Indomethacin (Indometacin)
Related Therapies and Procedures
1.
Injections