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Gal-VP16

a GAL4 protein coupled to herpes simplex virus encoded protein VP16; chimeric acid activator

Also Known As:

Gal4-VP16

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843

Experts

1.	Arendt, Maja L: 1 article (12/2009)
2.	Morgan, Iain M: 1 article (12/2009)
3.	Nasir, Lubna: 1 article (12/2009)
4.	Hattori, Yoshiyuki: 1 article (08/2006)
5.	Maitani, Yoshie: 1 article (08/2006)

Related Diseases

1.

Neoplasms (Cancer)

12/01/2009 - "VP16-E2 is superior to Gal4-VP16 as the transcriptional activator in a TSTA system driven by either of the two potentially cancer-specific promoters telomerase RNA and telomerase reverse transcriptase in several cell lines. "
08/01/2006 - "We designed a TSTA system and constructed two types of plasmid: one containing GAL4-VP16 fusion protein under the control of a tumor-specific promoter, the other containing luciferase or herpes simplex virus thymidine kinase (HSV-tk) under the control of a synthetic promoter. "

Related Drugs and Biologics

1.	tumor-associated transplantation antigen (TSTA)
2.	Telomerase (Telomerase Reverse Transcriptase)
3.	telomerase RNA (bTR)
4.	Thymidine Kinase
5.	Proteins (Proteins, Gene)
6.	Luciferases