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Subscribe to New Research on PA22-2
a 19-amino acid synthetic peptide; from the laminin A chain sequence
Also Known As:
CSRARKQAASIKVAVSADR-NH2; PA 22-2
relevant articles (
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins
11/01/1991 - "
As has been reported for many other tumor cells, laminin and the laminin-derived peptide PA22-2, containing the sequence IKVAV, mediate attachment of line 410.4 mammary tumor cells in vitro.
Neoplasm Metastasis (Metastasis)
01/01/1992 - "
Here we have exposed the clone 10 cells to the synthetic peptide PA22-2, which contains the IKVAV sequence from the A chain of laminin and which, like laminin, induces collagenase IV production and enhances metastasis formation by B16F10 cells.
Melanoma (Melanoma, Malignant)
06/01/1994 - "
However, the IKVAV containing PA22-2 laminin peptide selectively stimulated type IV collagenolytic activity of the A-2058 melanoma cell line, although it did not modulate MMP/TIMP activity.
Related Drugs and Biologics
Tissue Inhibitor of Metalloproteinases (TIMP)
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