CI 972

structure given in first source

Also Known As:

2,6-diamino-3,5-dihydro-7-(3-thienylmethyl)-4H-pyrrolo(3,2-d)pyrimidin-4-one; CI-972; 4H-Pyrrolo(3,2-d)pyrimidin-4-one, 2,6-diamino-1,5-dihydro-7-(3-thienylmethyl)-, monohydrochloride

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - CI 972: 2
  - Thiophenes: 257
    - CI 972: 2
Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiophenes: 257
    - CI 972: 2

Related Diseases

1.	Sarcoma (Soft Tissue Sarcoma) 09/29/2023 - "Sensitivity, specificity, positive and negative likelihood ratios, diagnostic odds ratio, and area under the curve on summary receiver operating characteristic were calculated for each included study and as pooled estimate, with 95% confidence interval (CI); 972 women (694 with uterine leiomyomas and 278 with uterine sarcomas) were included. "
2.	Leiomyoma (Uterine Fibroids) 09/29/2023 - "Sensitivity, specificity, positive and negative likelihood ratios, diagnostic odds ratio, and area under the curve on summary receiver operating characteristic were calculated for each included study and as pooled estimate, with 95% confidence interval (CI); 972 women (694 with uterine leiomyomas and 278 with uterine sarcomas) were included. "
3.	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 03/01/1994 - "To elucidate the potential use of PNP inhibitors in the therapy of cutaneous T-cell lymphomas (CTCLs) the authors studied the effects of CI-1000 (formerly PD141955-2) and CI-972 on a T-cell line MyLa established from a patient with mycosis fungoides. "
4.	Mycosis Fungoides 03/01/1994 - "To elucidate the potential use of PNP inhibitors in the therapy of cutaneous T-cell lymphomas (CTCLs) the authors studied the effects of CI-1000 (formerly PD141955-2) and CI-972 on a T-cell line MyLa established from a patient with mycosis fungoides. "

Related Drugs and Biologics

1.	9-deaza-9-(3-thienylmethyl)guanine

Related Therapies and Procedures

1.	Therapeutics