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alglucerase (Ceredase)

modified form of human placental glucocerebrosidase; oligosaccharide units of glucocerebrosidase are sequentially deglycosylated to yield a mannose-terminated preparation which is targeted to the mannose lectin on the macrophage plasma membrane
Also Known As:
Ceredase; Genzyme brand of alglucerase
Networked: 60 relevant articles (8 outcomes, 3 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Zimran, Ari: 3 articles (09/2014 - 02/2009)
2. vom Dahl, Stephan: 3 articles (05/2013 - 02/2009)
3. Charrow, Joel: 2 articles (05/2013 - 02/2009)
4. Cole, J Alexander: 2 articles (05/2013 - 02/2009)
5. Germain, D P: 2 articles (12/2010 - 11/2001)
6. Belmatoug, Nadia: 2 articles (11/2009 - 01/2002)
7. Kaplan, Paige: 2 articles (11/2009 - 12/2008)
8. Kacena, Katherine: 2 articles (02/2009 - 12/2008)
9. Yee, John: 2 articles (02/2009 - 12/2008)
10. Elstein, Deborah: 1 article (09/2014)

Related Diseases

1. Gaucher Disease (Gaucher's Disease)
2. Fabry Disease (Fabry's Disease)
3. Lysosomal Storage Diseases (Lysosomal Storage Disease)
4. Thrombocytopenia (Thrombopenia)
5. Neurologic Manifestations (Neurological Manifestations)

Related Drugs and Biologics

1. imiglucerase (Cerezyme)
2. alglucerase (Ceredase)
3. Glucosylceramidase (Glucocerebrosidase)
4. Glucosidases
5. Lysergic Acid Diethylamide (LSD)
6. agalsidase beta
7. agalsidase alfa
8. Mannose (D-Mannose)
9. Neutralizing Antibodies
10. Immunoglobulin G (IgG)

Related Therapies and Procedures

1. Enzyme Replacement Therapy
2. Enzyme Therapy
3. Transplants (Transplant)
4. Bone Marrow Transplantation (Transplantation, Bone Marrow)
5. Splenectomy