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RG 14620

structure given in first source

Also Known As:

RG-14620; 3-Pyridineacetonitrile, alpha-((3,5-dichlorophenyl)methylene)-

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzylidene Compounds: 10
        Tyrphostins: 183
        RG 14620: 2
- Nitriles: 227
  - Tyrphostins: 183
    - RG 14620: 2
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinoxalines: 324
      - Tyrphostins: 183
        RG 14620: 2

Experts

1.	Li, Xiao-mao: 1 article (09/2009)
2.	Shen, Hui-min: 1 article (09/2009)
3.	Wang, Xiao-yun: 1 article (09/2009)
4.	Xiao, Lan: 1 article (09/2009)
5.	Xu, Cheng-fang: 1 article (09/2009)
6.	Yang, Yue-bo: 1 article (09/2009)

Related Diseases

1.	Endometrial Neoplasms (Endometrial Cancer) 09/01/2009 - "The endometrial carcinoma cells (HEC-1A, HEC-1A-PTEN-null, Ishikawa, Ishikawa-PTEN) were treated with signal transduction inhibitors, RG-14620, SB203580 (SB) and rapamycin, respectively. "
2.	Psoriasis (Pustulosis Palmaris et Plantaris) 03/01/1994 - "Based on its epidermal growth factor receptor-mediated tyrosine kinase inhibitory activity, (Z)-alpha-[(3,5-dichlorophenyl)methylene]-3- pyridylacetonitrile (RG 14620) is undergoing evaluation as a topical drug for psoriasis. "

Related Drugs and Biologics

1.	ErbB Receptors (EGF Receptor)
2.	Sirolimus (Rapamycin)
3.	Protein-Tyrosine Kinases (Tyrosine Kinase)
4.	SB 203580