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(endo- N- 8- methyl- 8- azabicyclo- (3.2.1)oct- 3- yl)- 2,3- dihydro- 3- isopropyl- 2- oxo- 1H- benzimidazol- 1- carboxamide

potent agonist at the 5-HT(4) receptor positively coupled to adenylate cyclase in brain; structure given in first source

Also Known As:

BIMU 8

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Bridged-Ring Heterocyclic Compounds
  - Heterocyclic Bridged Bicyclo Compounds
    - (endo-N-8-methyl-8-azabicyclo-(3.2.1)oct-3-yl)-2,3-dihydro-3-isopropyl-2-oxo-1H-benzimidazol-1-carboxamide: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzimidazoles: 245
      - (endo-N-8-methyl-8-azabicyclo-(3.2.1)oct-3-yl)-2,3-dihydro-3-isopropyl-2-oxo-1H-benzimidazol-1-carboxamide: 1

Related Diseases

1.

Amnesia (Dissociative Amnesia)

09/01/1998 - "BIMU 1 (20 mg kg-1 i.p.) and BIMU 8 (30 mg kg-1 i.p.), administered 20 min before the training session, prevented the 5-HT4 receptor antagonist-induced amnesia. "
09/01/1998 - "In the same experimental conditions BIMU 1 (10 mg kg-1 i.p.; 25 microgram/mouse intracerebroventricularly) and BIMU 8 (30 mg kg-1 i.p.; 30 microgram per mouse intracerebroventricularly) prevented scopolamine (1 mg kg-1 i.p.) and dicyclomine (2 mg kg-1 i.p.) amnesia and, at the dose of 10 and 30 mg kg-1 i.p. "

Related Drugs and Biologics

1.	5-HT4 Serotonin Receptors
2.	Scopolamine (Hyoscine)
3.	Dicyclomine (Bentyl)
4.	(endo- N- 8- methyl- 8- azabicyclo(3.2.1)oct- 3- yl)- 2,3- dihydro- 3- ethyl- 2- oxo- 1H- benzimidazol- 1- carboxamide
5.	P-30 composite resin (P 30)