NSC 615985

structure given in first source; potent inhibitor of HIV reproduction

Also Known As:

2-chloro-5-((5,6-dihydro-2-methyl-1,4-oxathiin-3-yl)carbonylamino)benzoic acid 1-methylethyl ester; NSC-615985; UC84; Benzoic acid, 2-chloro-5-(((5,6-dihydro-2-methyl-1,4-oxathiin-3-yl)carbonyl)amino)-, 1-methylethyl ester

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Aniline Compounds: 46
    - Anilides: 22
      - Carboxin: 5
        NSC 615985: 2
- Amides: 2428
  - Anilides: 22
    - Carboxin: 5
      - NSC 615985: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Oxathiins
    - Carboxin: 5
      - NSC 615985: 2

Experts

1.	Motakis, Dimitrios: 1 article (06/2002)
2.	Parniak, Michael A: 1 article (06/2002)

Related Diseases

1.	Infections 06/01/2002 - "Pretreatment of uninfected lymphocytoid cells with UC781, EFV, or CSIC, but not DLV, NVP, or UC84, protected these cells from subsequent HIV-1 infection in the absence of extracellular drug. "
2.	Acquired Immunodeficiency Syndrome (AIDS) 05/01/1998 - "NSC 615985 (UC 84) has demonstrated anti-HIV activity in the NCI-AIDS antiviral screen and was under consideration as an anti-AIDS drug. "

Related Drugs and Biologics

1.	Anti-HIV Agents (AIDS Drugs)
2.	Antiviral Agents (Antivirals)
3.	UC-781