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diadenosine 5',5''''-P1,P6-hexaphosphate

inhibits the action of ribonuceotide reductase on ADP

Also Known As:

Ap(6)A; Ap6A; P1,P6-di(adenosine-5')hexaphosphate; diadenosine hexaphosphate

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
  - Dinucleoside Phosphates: 4
    - diadenosine 5',5''''-P1,P6-hexaphosphate: 2

Experts

1.	Ganschow, Rainer: 1 article (08/2002)
2.	Grabhorn, Enke: 1 article (08/2002)
3.	Lemke, Joachim: 1 article (08/2002)
4.	Lepler, Rudolf: 1 article (08/2002)
5.	Barenbrock, M: 1 article (02/2001)
6.	Hausberg, M: 1 article (02/2001)
7.	Hollah, P: 1 article (02/2001)
8.	Kosch, M: 1 article (02/2001)
9.	Letzel, M: 1 article (02/2001)
10.	Rahn, K H: 1 article (02/2001)

Related Diseases

1.	Essential Hypertension 02/01/2001 - "The study shows that thrombocyte concentrations of AP5A and AP6A are elevated in patients with essential hypertension. "
2.	Tachycardia (Tachyarrhythmias) 08/01/2002 - "We hypothesize that decreased concentrations and receptor binding of serum and tissue diadenosine polyphosphates, such as AP4A, AP5A, or AP6A, which are stored in various tissues and serve as extra-cellular signaling molecules or are secreted by cells in response to physiologically stressful stimuli, lead to the observed severe tachyarrhythmia. "

Related Drugs and Biologics

1.	P(1),P(5)- di(adenosine- 5'- )pentaphosphate
2.	Polyphosphates
3.	diadenosine tetraphosphate