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gamma- (2- aminoethylamino)- 2- butryothienone

structure given in first source; RN from Toxlit

Also Known As:

gamma-ABT

Networked: 2 relevant articles (2 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiophenes: 257
    - gamma-(2-aminoethylamino)-2-butryothienone: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Thiophenes: 257
    - gamma-(2-aminoethylamino)-2-butryothienone: 2

Related Diseases

1.	Body Weight (Weight, Body) 05/01/1991 - "gamma-ABT improved the change in albumin/globulin ratio, which is a parameter of systemic inflammatory reaction but did not improve the body weight gain in AID and normal rats. "
2.	Autoimmune Diseases (Autoimmune Disease) 04/01/1991 - "gamma-ABT posses in addition the advantage of antioxidant activity which is not shared by selective cyclooxygenase inhibitors and thus should be potentially effective in autoimmune diseases."
3.	Inflammation (Inflammations) 05/01/1991 - "The effect of the novel agent gamma-(2-aminoethylamino)-2-butyrothienone (gamma-ABT) on local and systemic changes of rats with adjuvant induced disease (AID) was investigated, gamma-ABT showed potent inhibitory effect on adjuvant primary inflammation and almost totally inhibited the secondary lesions. " 04/01/1991 - "In conclusion gamma-ABT is an effective agent not only on acute but also on subacute and chronic inflammation and its mode of action appears similar to other NSAID. "
4.	Edema (Dropsy) 04/01/1991 - "gamma-ABT inhibited as well the sustained edema induced by mustard. " 04/01/1991 - "Similarly to indometacin, gamma-ABT inhibited the early and late stage of yeast-induced edema in contrast to concanavalin A (Con A) induced edema which was only inhibited by gamma-ABT. " 04/01/1991 - "The inhibitory effect of gamma-ABT on carrageenin-induced edema was remarkable and nearly equal to that of indometacin. " 04/01/1991 - "gamma-ABT displayed an inhibitory effect on nystatin-induced edema similar to indometacin suggesting that gamma-ABT has significant membrane stabilizing action and a strong blocking action on synthesis of prostaglandins. "

Related Drugs and Biologics

1.	Cyclooxygenase Inhibitors
2.	Globulins
3.	Antioxidants
4.	Albumins
5.	Prostaglandins
6.	Nystatin (Mycostatin)
7.	Indomethacin (Indometacin)
8.	Concanavalin A
9.	Carrageenan
10.	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)