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cecropin P1-LI

antibacterial peptide isolated from porcine intestine; has immunoreactivity in epithelial cells of duodenum & glucagon cells of the pancreas

Also Known As:

cecropin P1; porcine cecropin

Networked: 9 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - cecropin P1-LI: 9

Experts

1.	Chen, Thomas T: 2 articles (06/2019 - 10/2018)
2.	Han, Yueh-Chiang: 2 articles (06/2019 - 10/2018)
3.	Lin, Chun-Mean: 1 article (10/2018)
4.	Chen, Yaosheng: 1 article (11/2014)
5.	Cong, Peiqing: 1 article (11/2014)
6.	Guo, Chunhe: 1 article (11/2014)
7.	He, Zuyong: 1 article (11/2014)
8.	Huang, Yumao: 1 article (11/2014)
9.	Liu, Xiaohong: 1 article (11/2014)
10.	Abbott, Nicholas L: 1 article (06/2014)

Related Diseases

1.	Septic Shock (Toxic Shock Syndrome) 09/01/2001 - "To investigate the efficacy of three cecropins, cecropin A, cecropin B, and cecropin P1, in preventing lethality in a rat model of septic shock. "
2.	Infections 06/01/2019 - "Recently, our laboratory had produced five families of transgenic rainbow trout harboring cecropin P1 transgene, and via repeated challenge studies these fish exhibited a significant elevation of resistance to infection by microbial pathogens. " 10/19/2018 - "Therefore, we hypothesized that cecropin P1 may not only eliminate pathogens directly, but also modulate the host immune systems, leading to increased resistance against pathogen infections. " 11/18/2014 - "The aim of this study was to evaluate the inhibitory effects and underlying molecular mechanisms of the antimicrobial peptide cecropin P1 (CP1) against PRRSV infection in vitro. " 11/01/2009 - "This study reports that Escherichia coli phosphatidylcholine-positive (PC+) strain Top10/ptac66 (PC+ PE+), in which borrelial PC synthase (PCS) directly condenses exogenous choline with CDP-diacylglycerol (CDP-DAG) to form PC, displayed not only stronger resistance to antimicrobial peptides cecropin P1 and indolicidin, but also decreased ability to attract macrophages to the abdominal cavity of infected mice in the 36 h following infection, compared with the control strain Top10/ptac85 (PC- PE+). "
3.	Inflammation (Inflammations) 06/01/2023 - "Overall, our results indicate that cecropin P1 exhibits pro-inflammation activity, modulate cell-cell interaction and cytokine signal transduction in rainbow trout gill cell, and may suggest a potential application of this peptide as an immune adjuvant for disease control in aquaculture." 06/01/2023 - "The dose-response study revealed significant perturbations of mRNA levels of genes related to pro-inflammation, acute phase, surface proteins and transcription factors at 30 μM of cecropin P1. "
4.	Whooping Cough (Pertussis) 04/01/1996 - "pertussis BP338 was more resistant than the avirulent bvg mutant strain BP347 and the brk mutant strain BPM2041 to killing by cecropin P1. "
5.	Cysts 08/01/1998 - "At a concentration of 66.77 mg/L, cecropin P1 produced a 93.3% and 98.1% reduction in cyst and trophozoite counts, respectively, while magainin II at a concentration of 49.33 mg/L produced a 90.6% and 98.7% reduction in cyst and trophozoite counts, respectively. "

Related Drugs and Biologics

1.	cecropin A
2.	Cecropins
3.	Insecta cecropin B protein
4.	Antimicrobial Peptides
5.	Transcription Factors (Transcription Factor)
6.	Messenger RNA (mRNA)
7.	Phosphatidylcholines (Phosphatidylcholine)
8.	Membrane Proteins (Integral Membrane Proteins)
9.	Cytidine Diphosphate Diglycerides (CDP-Diacylglycerol)
10.	Cytidine Diphosphate (CDP)