L-selectin counter-receptors

in mesenteric lymph nodes, Peyer's patches, and high endothelial venules, sometimes found bound to MAdCAM-1

Also Known As:

L-selectin counter-receptor; MECA 79; MECA-79 antigen; PNAd antigen; peripheral lymph node addressin; vascular addressins

Networked: 29 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Biological Factors: 2472
- Antigens: 143924
  - Surface Antigens: 5813
    - L-selectin counter-receptors: 29
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - L-selectin counter-receptors: 29

Experts

1.	Kobayashi, Motohiro: 6 articles (04/2019 - 12/2004)
2.	Nakayama, Jun: 5 articles (01/2013 - 12/2004)
3.	Fukuda, Minoru: 4 articles (05/2009 - 12/2004)
4.	Hoshino, Hitomi: 2 articles (04/2019 - 07/2007)
5.	Sakai, Yasuhiro: 2 articles (01/2013 - 07/2007)
6.	Lee, Heeseob: 2 articles (05/2009 - 01/2009)
7.	Cho, Arthur: 1 article (01/2022)
8.	Kim, Honsoul: 1 article (01/2022)
9.	Park, Seung Hyun: 1 article (01/2022)
10.	Ryu, Hyang Joo: 1 article (01/2022)

Related Diseases

1.	Nasal Polyps (Nasal Polyp) 04/01/2019 - "In the present study, we carried out quantitative immunohistochemical analysis of nasal polyps associated with ECRS (n=30) and non-ECRS (n=30) to evaluate expression of an L-selectin ligand peripheral lymph node addressin (PNAd) on vascular endothelial cells. "
2.	Autoimmune Pancreatitis 01/01/2013 - "The present study was undertaken to determine whether vascular addressins including peripheral lymph node addressin and mucosal addressin cell adhesion molecule 1 (MAdCAM-1) play a role in type 1 AIP histogenesis. "
3.	Neoplasms (Cancer) 10/01/2014 - "MECA-79(+) HEV-like venules were observed in the neighborhood of the follicles in the majority of cases, however, their presence was not confined to tumors hosting ectopic lymphoid structures. " 12/01/1991 - "Furthermore, tumors expressed human LFA-1/ICAM-1 and the tumor blood vessels strongly expressed murine ICAM-1, but not MECA 79. " 09/01/2011 - "In this article, we report the presence of MECA 79(+) blood vessels displaying all the phenotypic characteristics of HEVs in most of the 319 human primary solid tumors, including melanomas, breast, ovarian, colon, and lung carcinomas, analyzed. " 06/01/1995 - "Tumor vasculature showed signs of activation in each patient on the basis of elevated levels of intercellular adhesion molecule-1, E-selectin, vascular cell adhesion molecule-1, and/or peripheral lymph node addressin (PNAd). "
4.	Inflammation (Inflammations) 12/01/1993 - "The extravasation of blood-borne lymphocytes into organized lymphoid tissues and sites of chronic inflammation is directed in part by interactions of lymphocyte surface adhesion molecules, known as homing receptors, with tissue-selective endothelial ligands called vascular addressins. " 12/02/2022 - "Immunoglobulin family and carbohydrate vascular addressins encoded by Madcam1 and St6gal1 control lymphocyte homing into intestinal tissues, regulating immunity and inflammation. " 12/01/1994 - "Because MECA 79 stains HEV-like vessels at various sites of inflammation, recognition by L-selectin of ligands outside of secondary lymphoid organs may depend on sulfation. " 05/01/2001 - "The adhesiveness of HEV ligands for L-selectin and alpha4beta7 integrin (ie, peripheral lymph node addressin and mucosal addressin cell adhesion molecule-1) also increased during WBH or febrile responses associated with lipopolysaccharide-induced or turpentine-induced inflammation. "
5.	Gastritis 11/01/1997 - "pylori-associated follicular gastritis and MALT lymphomas high endothelial venules coexpressed mucosal addressin cell adhesion molecule-1 and peripheral lymph node addressin. " 01/01/2009 - "In chronic gastritis, lymphocytes infiltrate the lamina propria, and such infiltration is facilitated by 6-sulfo sialyl Lewis X-capped O-glycans, peripheral lymph node addressin (PNAd), on high endothelial venule (HEV)-like vessels. " 05/01/2009 - "In chronic gastritis, lymphocytes infiltrate the lamina propria, and such infiltration is facilitated by the interaction between L-selectin on lymphocytes and peripheral lymph node addressin (PNAd), which contains 6-sulfo sialyl Lewis X-capped O-glycans, on high endothelial venule (HEV)-like vessels. "

Related Drugs and Biologics

1.	L-selectin counter-receptors
2.	L-Selectin
3.	Ligands
4.	Cell Adhesion Molecule-1
5.	N 30
6.	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)
7.	6-sulfo sialyl Lewis X
8.	Lymphocyte Homing Receptors
9.	Polysaccharides (Glycans)
10.	beta Catenin