norcantharidin

04/01/2010 - "These in vitro results suggest that norcantharidin may be a safe and effective anti-cancer drug for CRC."
07/01/2018 - "Recent studies have demonstrated that norcantharidin (NCTD) can inhibit the proliferation and migration of various human cancer cells, but the role of NCTD in GCTB has not previously been evaluated. "
01/12/2018 - "Previous studies reported that norcantharidin (NCTD) has anti-tumor effects. "
11/27/2023 - "Norcantharidin (NCTD), an active ingredient in traditional Chinese medicines, possesses activity against different cancers. "
01/01/2022 - "Norcantharidin promotes cancer radiosensitization through Cullin1 neddylation-mediated CDC6 protein degradation."

01/01/2016 - "The diacid metabolite of norcantharidin (DM-NCTD) is clinically effective against hepatocellular carcinoma (HCC), but is limited by its short half-life and high incidence of adverse effects at high doses. "
01/01/2021 - "Treatment for Hepatocellular Carcinoma Is Enhanced When Norcantharidin Is Encapsulated in Exosomes Derived from Bone Marrow Mesenchymal Stem Cells."
12/11/2017 - "Author Correction: FAM46C is critical for the anti-proliferation and pro-apoptotic effects of norcantharidin in hepatocellular carcinoma cells."
08/01/2017 - "Norcantharidin inhibits IL-6-induced epithelial‑mesenchymal transition via the JAK2/STAT3/TWIST signaling pathway in hepatocellular carcinoma cells."
01/01/2017 - "Norcantharidin combined with Coix seed oil synergistically induces apoptosis and inhibits hepatocellular carcinoma growth by downregulating regulatory T cells accumulation."

01/01/2021 - "In our previous study, we demonstrated that norcantharidin (NCTD) is a potential therapeutic agent for renal interstitial fibrosis (RIF). "
01/01/2021 - "Anti-renal interstitial fibrosis effect of norcantharidin is exerted through inhibition of PP2Ac-mediated C-terminal phosphorylation of Smad3."
11/01/2020 - "Norcantharidin protects against renal interstitial fibrosis by suppressing TWEAK-mediated Smad3 phosphorylation."
01/01/2015 - "Norcantharidin (NCTD) has been proven to be able to attenuate renal interstitial fibrosis, but the exact molecular mechanism is still unknown. "
01/01/2015 - "Norcantharidin inhibits renal interstitial fibrosis by downregulating PP2Ac expression."

01/01/2017 - "Therefore, our study was designed to determine the efficacy of norcantharidin on SK-N-SH neuroblastoma cell death and to elucidate detailed mechanisms of activity. "
01/01/2017 - "However, the anticancer activities of norcantharidin with respect to neuroblastoma, and its underlying mechanisms, have not been investigated. "
01/01/2017 - "Norcantharidin Inhibits SK-N-SH Neuroblastoma Cell Growth by Induction of Autophagy and Apoptosis."
08/01/2014 - "Norcantharidin enhances ABT-263-mediated anticancer activity in neuroblastoma cells by upregulation of Noxa."
01/01/2017 - "Thus, the traditional Chinese medicine norcantharidin could be a novel therapeutic strategy for treating neuroblastoma."

01/01/2018 - "Although norcantharidin (NCTD) is effective in primary liver cancer treatment, its toxicity in the urinary system remains. "
07/14/2021 - "Norcantharidin (NCTD) is suitable for the treatment of primary liver cancer, especially early and middle primary liver cancer. "
08/10/2010 - "To elucidate the molecular mechanism of norcantharidin (NCTD) in inducing apoptosis of liver cancer cells so as to provide basic rationales for its application in liver cancer treatment. "
08/10/2010 - "[Molecular mechanism of norcantharidin inducing apoptosis in liver cancer cells]."
01/01/1996 - "These result simply that Norcantharidin may have a role to play in the chemotherapy of primary liver cancer."