3-hydroxymexiletine

metabolite of mexiletine; structure given in first source

Also Known As:

1-(2,6-dimethyl-3-hydroxyphenoxy)-2-aminopropane; m-hydroxymexiletine; meta-hydroxymexiletine

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Colabufo, Nicola Antonio: 1 article (10/2015)
2.	Contino, Marialessandra: 1 article (10/2015)
3.	Defrenza, Ivana: 1 article (10/2015)
4.	Gualdani, Roberta: 1 article (10/2015)
5.	Lentini, Giovanni: 1 article (10/2015)
6.	Roselli, Mariagrazia: 1 article (10/2015)
7.	Tadini-Buoninsegni, Francesco: 1 article (10/2015)

1.	Cardiac Arrhythmias (Arrythmia) 10/01/2015 - "Looking for a possible mexiletine alternative, we show that m-hydroxymexiletine (MHM), a minor mexiletine metabolite recently reported to be as active as the parent compound in an arrhythmia animal model, is a weaker hERG channel blocker, compared to mexiletine (IC50 = 22.4 ± 1.2 μmol/L). "

1.	Mexiletine (Mexitil)