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YM 13650
structure given in first source; RN from Toxlit
Also Known As:
2-(3-carboxyacetoxyphenyl)imidazo(2,1-b)benzothiazole; YM-13650
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Thiazoles: 392
Benzothiazoles: 40
YM 13650: 2
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Benzothiazoles: 40
YM 13650: 2
Related Diseases
1.
Shock
02/01/1991 - "
On the other hand, YM-13650 did not show any inhibitory effect on passive cutaneous anaphylaxis in rats (type I), Forssman shock in guinea pigs (type II) and carrageenin-induced paw edema in rats.
"
2.
Proteinuria
04/01/1991 - "
In preventative experiments in lupus mice treated from 8 weeks of age, YM-13650 in comparison with the control group showed a lesser degree of proteinuria throughout the experimental period.
"
3.
Nephritis
04/01/1991 - "
[Effects of YM-13650 on experimental nephritis in rats and mice].
"
04/01/1991 - "
These results show that YM-13650 has preventative and therapeutic effects on experimental nephritis in rats and mice, and it may prove valuable as an anti-nephritic drug.
"
04/01/1991 - "
We investigated the effects of YM-13650, 2-(m-carboxyacetoxyphenyl) imidazo [2, 1-b] benzothiazole, on BSA-immune complex nephritis in rats and lupus nephritis in NZB/W F1 mice.
"
04/01/1991 - "
In preventative experiments on immune complex nephritis in rats, YM-13650 (10 approximately 100 mg/kg, p.o.) dose-dependently inhibited the increase in urinary protein, serum cholesterol, and urea nitrogen.
"
4.
Lupus Nephritis
04/01/1991 - "
We investigated the effects of YM-13650, 2-(m-carboxyacetoxyphenyl) imidazo [2, 1-b] benzothiazole, on BSA-immune complex nephritis in rats and lupus nephritis in NZB/W F1 mice.
"
5.
Hypersensitivity (Allergy)
02/01/1991 - "
These results indicate that YM-13650 suppresses not only cell-mediated immune responses but also type III allergic reactions without any influence on type I and type II allergic reactions as well as an acute inflammatory reaction.
"
02/01/1991 - "
YM-13650 in the dose range of 6.3 to 100 mg/kg, p.o., inhibited the picrylchloride-induced delayed type hypersensitivity (Pc-DTH) in mice when administered during the induction and the effector phases.
"
02/01/1991 - "
The effects of YM-13650 on experimental animal models of cell-mediated immune responses (type IV), antibody formation and type I to type III allergic reactions were investigated.
"
02/01/1991 - "
[Effects of YM-13650 on type I to type IV allergic reactions and immune responses in animals].
"
Related Drugs and Biologics
1.
Therapeutic Uses
2.
Urea (Carbamide)
3.
Nitrogen
4.
Cholesterol
5.
Carrageenan
6.
Blood Proteins (Serum Proteins)
7.
Antigen-Antibody Complex (Immune Complex)
8.
benzothiazole