lophirone A

from Lophira alata; RN given from CA Abstr Index Guide 1990; RN given refers to (+-)-isomer; RN for cpd without isomeric designation not avail 7/91; structure given in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Atilaw, Yoseph: 1 article (06/2021)
2.	Bourgard, Catarina: 1 article (06/2021)
3.	Erdelyi, Mate: 1 article (06/2021)
4.	Gilissen, Pieter J: 1 article (06/2021)
5.	Kalenga, Thobias M: 1 article (06/2021)
6.	Munissi, Joan J E: 1 article (06/2021)
7.	Ndoile, Monica M: 1 article (06/2021)
8.	Nyandoro, Stephen S: 1 article (06/2021)
9.	Rudenko, Anastasia: 1 article (06/2021)
10.	Sunnerhagen, Per: 1 article (06/2021)

Related Diseases

1.	Neoplasms (Cancer) 06/14/1991 - "Application of lophirone A (160 nmol) reduced the number of tumors per mouse (IE = 85%) in an initiation-promotion experiment using dimethylbenz[a]anthracene (DMBA, 0.19 mumol) and TPA (1.6 nmol) on ICR mouse skin. " 06/14/1991 - "Lophirone A, isolated as a new type of biflavonoid-related inhibitor of Epstein-Barr virus (EBV) activation, was tested for further inhibitory properties against tumor promotion by short-term system. "
2.	Inflammation (Inflammations) 06/14/1991 - "Lophirone A (200 micrograms) significantly inhibited inflammation of mouse ear (inhibitory effect (IE) = 70%) by 12-O-hexadecanoyl-16-hydroxyphorbol-13-acetate (HHPA, 2 micrograms). "
3.	Breast Neoplasms (Breast Cancer) 06/01/2021 - "Out of the eight isolated natural products, calodenin B (4) and lophirone A (6) showed significant antibacterial activity against the Gram-positive bacterium Bacillus subtilis with MIC values of 2.2 and 28 μM, and cytotoxicity against the MCF-7 human breast cancer cell line with EC50 values of 219.3 and 19.2 μM, respectively. "

Related Drugs and Biologics

1.	Biflavonoids
2.	anthracene
3.	croton factor F1